抄録
During the period from 1957 to 1959, many strains ofBord. bronchisepticawere isolated from the guinea pigs used for the safety test of biological products. Particularly, from winter to spring, the organisms were frequently obtained, but neither significant symptoms nor death was observed among these infected guinea pigs.
In regards to feeding and administration of laboratory animals, however, it is no doubtedly important that guinea pigs should be controlled against these quiescent infectious agents.
From the results of our inoculation test, in which guinea pigs were inoculated intranasally with the fresh culture ofBord. bronchiseptica, or with the emulsion of the locus of pneumonia of guinea pig, we have confirmed thatBord. bronchisepticawas a causative agent of the pneumonia described here.