Abstract
With the development of biotechnology in recent years, its application areas have expanded beyond the traditional fields of fermentation and brewing to a variety of areas in the bio-industry. An indispensable technological field in biotechnological manufacturing is "baiyo". The Japanese word "baiyo" is translated as "culture" or "cultivation" in English. The English word culture includes way of life, art, and customs, the attitudes and beliefs and the practice of growing crops or fish, and other concepts not found in the Japanese word "baiyo". The Japanese word "baiyo" is an expression unique to the Japanese language that mainly refers to the propagation of "cells" as the basic unit in an artificial environment, and clearly refers to the cultivation (increase) of organisms (cells) for some purpose by humans. This special issue focuses on the cultivation of cells, from case studies to human resource development. I hope that readers will understand the fun, difficulty, and pleasure of manufacturing through "baiyo" as well as the importance of human resource development.