1994 年 60 巻 6 号 p. 687-689
Diarrhetic shellfish toxins in mussels collected from the Adriatic coast of Italy were analyzed by both mouse bioassay and fluorometric high performance liquid chromatography (HPLC). Of eleven specimens tested, one each from Trieste, Rimini, and Ancona proved to be toxic in the mouse bioassay. In each case, okadaic acid was confirmed as the major toxin by HPLC analysis, but in addition to okadaic acid, unprecedented toxins having cytotoxic activity were found to be present in a Rimini sample.