FUKUSHIMA JOURNAL OF MEDICAL SCIENCE
Online ISSN : 2185-4610
Print ISSN : 0016-2590
ISSN-L : 0016-2590
A survey of pathological amenorrhea in fukushima prefecture, with a focus on turner syndrome
Akiko Yamaguchi, Hiromi Yoshida-Komiya, Toshifumi Takahashi, Mayumi Noguchi, Keiya Fujimori, the Fukushima Prefecture Obstetrics and Gynecology Association
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JOURNAL OPEN ACCESS FULL-TEXT HTML Advance online publication
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Article ID: 26-00025

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Abstract

Lifelong health management is important for women with pathological amenorrhea. We investigated the number of outpatient visits in Fukushima Prefecture by patients with pathological amenorrhea and evaluated the etiology and management of the condition. Questionnaires were sent to facilities affiliated with Fukushima Obstetrics and Gynecology Association from October 2021 to September 2022. The patients were 15-45 years old. Turner syndrome was the most common cause of primary amenorrhea (43.4%), whereas polycystic ovary syndrome was the most common cause of secondary amenorrhea (47.7%). Most cases with Turner syndrome received management at a general hospital (50.6%). Almost half of the cases had complications. All cases with Turner syndrome received hormonal medication. Transdermal estrogen (43%) was the most used estrogen preparation, followed by combined estrogen tablets (40%). For progestin administration, dydrogesterone was the most commonly prescribed (43%), followed by medroxyprogesterone (37%). In managing cases with pathological amenorrhea, obstetrics and gynecology departments must establish future follow-up systems to fulfill their role as comprehensive healthcare providers for women. This involves collaborating with allied health professionals and relevant pediatric and internal medicine departments, as well as hormone replacement therapy.

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© 2026 The Fukushima Society of Medical Science

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