Nippon Yakubutsugaku Zasshi (Folia Pharmacologica Japonica)
Online ISSN : 2185-307X
Print ISSN : 0369-4461
ISSN-L : 0369-4461
On the Influence of Alcohol upon the Urinary Secretion.
Juji Okuto
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1926 Volume 2 Issue 1 Pages 70-83,en4

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Abstract
In order to examine the influence of alcohol upon the urinary secretion, the author has carried out a large number of experiments on rabbits and obtained the following results :
Intravenous injection of a small quantity of ethyl-alcohol, especially with a large amount of Ringei-Locke's solution, exerts an evident diuretic action, while a large amount of it cannot augment the flow of urine, but markedly diminishes it. In the peroral administration the alcohol diuresis only then occurs when abundant water has been given. When injected into the vein, alcohol in small doses causes a slight increase of the arterial pressure together with a scant augmentation of the volume of the kidneys, but in large doses these become entirely reversed.
From these facts the author would believe that an ample supply of water together with alcohol is the most important factor for alcohol diuresis.
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