Abstract
Infusing the physiological salt solution of various temperatures, i. e. 5°, 10°, 20°, 30°, 38°, 45°, 50°, 55° and 60°, into the veins of rabbits until they died, the author obtained the following facts :
1. When the physiological salt solution to be infused is of the body temperature animals can tolerate the greatest amount of it. With increase or decrease of its temperature from the body temperature, however, the fatal infusion quantity is markedly diminished.
2. The body temperature of animals is influenced by the abnormal temperature of the fluid infused, and changes itself the more as the difference between the temperatures of the body and of the fluid increases. The change of the body temperature is, however, then considerable when the infusion is carried out with a cold fluid.
3. In the infusion with a fluid the temperature of which is different from the body temperature over a certain extent, the urinary secretion is reduced, and this is especially marked with a cold fluid, so that in some extreme cases anuria occurs.4. No marked changes in the blood pressure can be seen even when a very hot or cold fluid (10° or 55°) is infused. But the respiration is quickened at first, and with the extremely cold infusion a transitory apnoea which repeats itself periodically is observed.
5. Whatever is the temperature of the fluid, after the infusion of a great quantity of it considerable venous stagnation and oedema are always observed. It is also noticeable that with the hot infusion marked haemorrhages in various organs (lungs, kidneys and intestines), and with the cold infusion an evident parenchymatous degeneration in the kidneys, are found.
