日本薬理学雑誌
Online ISSN : 1347-8397
Print ISSN : 0015-5691
ISSN-L : 0015-5691
合成抗痙攣藥に關する研究
第1報 3-(2'-Methyl phenoxy) propane-1, 2-diol並びに3-(2'-Methoxy phenoxy) propane-1, 2-diolの藥理作用について
大味谷 輝男
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1953 年 49 巻 2 号 p. 112-118,en12

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The muscle-relaxing potency and anticonvulsant activity against the convulsions induced by strychnine, picrotoxin and metrazol were conparatively studied with 3- (2'-methylphenoxy) -propane-1, 2-dial (Myanesin) and 3- (2'-methoxyphenoxy) -propane-1, 2diol (Hustosil) in white mice. Result : Against strychnine revealed Myanesin the most powerful anticonvulsant activity, while, Hustosil did against metrazol convulsion. As to the anti. convulsant activity against picrotoxin both of these drugs was relatively weak and just resembled in its degree each other.
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