日本薬理学雑誌
Online ISSN : 1347-8397
Print ISSN : 0015-5691
ISSN-L : 0015-5691
実験的鞭打ち損傷の研究(III)
頸髄の酵素活性の変動と鹿茸抽出物Pantocrinの効果
瀧川 勝雄国分 信彦梶原 大義土肥 美恵田原 溶夫
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1972 年 68 巻 4 号 p. 489-493

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Using rabbits and rats injured in experimental Whiplash, changes in glycolysis and enzyme activities of the cervical cords, and the effects of Pantui extracts, Pantocrin were investigated in detail.
In the cervical cords, depressed glycolysis and lowered activities of aldolase, GOT, and alkaline phosphatase were noted.
Cervical injuries were greater in rats than rabbits while hexokinase, glycerokinase and GPT were inhibited. Three enzymes in the rabbits were also inhibited. This enzymological difference between the two species appeared to be dependent on the extent of injury.
Pantocrin remarkably improved abnormal glycolysis and the lowered enzyme activities of cervical cords from both injured animals.

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