Abstract
The author investigated the effects of arsenite on pregnancy, birth and growth in rats that had been fed various diets containing various doses of arsenite, that is 10, 50 and 100 ppm. Results are as follows: 1) Female rats were fed a diet containing arsenite during pregnancy and the number of suckling from these females did not vary from that of the control group. 2) Female rats were fed a diet containing arsenite during pregnancy and thoughout the period of suckling their young. The young were fed a normal diet for 12 weeks after weaning. The offspring showed no effects of arsenite and appeared well nourished. 3) Female rats were fed a diet containing 100 ppm of arsenite during pregnancy and throughout the suckling period. The young were kept on the same diet for 12 weeks after weaning, but effects of arsenite on the hard tissue were not observed. Pathological changes in the organs of this experimental group were absent.
