Methylmercury induces expression of interleukin-1β and interleukin-19 in mice brains

Tsutomu Takahashi; Miyuki Iwai-Shimada; Yukina Syakushi; Min-Seok Kim; Gi-Wook Hwang; Nobuhiko Miura; Akira Naganuma

doi:10.2131/fts.2.239

Letter

Methylmercury induces expression of interleukin-1β and interleukin-19 in mice brains

Tsutomu Takahashi, Miyuki Iwai-Shimada, Yukina Syakushi, Min-Seok Kim, Gi-Wook Hwang, Nobuhiko Miura, Akira Naganuma

Author information

Tsutomu Takahashi
Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University
Department of Environmental Health, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences
Miyuki Iwai-Shimada
Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University
Yukina Syakushi
Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University
Min-Seok Kim
Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University
Gi-Wook Hwang
Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University
Nobuhiko Miura
Division of Health Effects Research, Japan National Institute of Occupational Safety and Health
Akira Naganuma
Laboratory of Molecular and Biochemical Toxicology, Graduate School of Pharmaceutical Sciences, Tohoku University

Keywords: Methylmercury, Brain, Interleukin, IL-1β, IL-19

JOURNAL FREE ACCESS

2015 Volume 2 Issue 6 Pages 239-243

DOI https://doi.org/10.2131/fts.2.239

Details

Abstract

We examined the effect of methylmercury administration on expression of interleukin genes in brain of mice. We found that gene expression of IL-1β and IL-19 was increased in the brain after the administration of methylmercury.

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