早期未分化型胃癌の増殖能に影響を与える因子の検討

中島 ひろみ; 廣岡 大司; 川野 潔; 依岡 伸幸; 小柴 良司; 久松 美友紀; 間島 行則; 益岡 優; 上田 栄寿; 川村 実里; 武田 修身; 半野 元; 高柳 成徳; 廣岡 知臣; 田口 牧子; 土細工 利夫

doi:10.11280/gee.59.2500

ANALYSIS OF FACTORS AFFECTING THE PROLIFERATIVE ACTIVITY OF EARLY UNDIFFERENTIATED GASTRIC CANCER

Hiromi NAKAJIMA , Takashi HIROOKA, Kiyoshi KAWANO, Nobuyuki YORIOKA, Ryouji KOSHIBA, Miuki HISAMATSU, Yukinori MASHIMA, Yuu MASUOKA, Yoshinori UEDA, Minori KAWAMURA, Osami TAKEDA, Hajime HANNNO, Shigenori TAKAYANAGI, Tomoomi HIROOKA, Makiko TAGUCHI, Toshio DOZAIKU

Author information

Hiromi NAKAJIMA Corresponding author
Department of Gastroenterology, Seichokai Fuchu Hospital.
Takashi HIROOKA
Department of Gastroenterology, Seichokai Fuchu Hospital.
Kiyoshi KAWANO
Department of Pathology, Seichokai Fuchu Hospital.
Nobuyuki YORIOKA
Department of Gastroenterology, Seichokai Fuchu Hospital.
Ryouji KOSHIBA
Department of Gastroenterology, Seichokai Fuchu Hospital.
Miuki HISAMATSU
Department of Gastroenterology, Seichokai Fuchu Hospital.
Yukinori MASHIMA
Department of Gastroenterology, Seichokai Fuchu Hospital.
Yuu MASUOKA
Department of Gastroenterology, Seichokai Fuchu Hospital.
Yoshinori UEDA
Department of Gastroenterology, Seichokai Fuchu Hospital.
Minori KAWAMURA
Department of Gastroenterology, Seichokai Fuchu Hospital.
Osami TAKEDA
Department of Gastroenterology, Seichokai Fuchu Hospital.
Hajime HANNNO
Department of Gastroenterology, Seichokai Fuchu Hospital.
Shigenori TAKAYANAGI
Department of Gastroenterology, Seichokai Fuchu Hospital.
Tomoomi HIROOKA
Department of Gastroenterology, Seichokai Fuchu Hospital.
Makiko TAGUCHI
Department of Gastroenterology, Seichokai Fuchu Hospital.
Toshio DOZAIKU
Department of Gastroenterology, Seichokai Fuchu Hospital.

JOURNAL FREE ACCESS FULL-TEXT HTML

2017 Volume 59 Issue 10 Pages 2500-2507

DOI https://doi.org/10.11280/gee.59.2500

Details

Abstract

[Background and purpose]

The aim of this study was to investigate factors affecting the proliferative activity of early undifferentiated gastric cancer.

[Method]

We investigated endoscopic and pathological features of early undifferentiated gastric cancer (74 lesions in 73patients). We used Ki-67 staining to evaluate the proliferative activity and identified factors affecting the proliferative activity.

[Results]

H.pylori infection was significantly associated with high Ki-67 index.

[Conclusion]

H. pylori infection may increase the proliferative activity of early undifferentiated gastric cancer.

Corresponding author

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