2017 Volume 59 Issue 7 Pages 1499-1506
An 84-year-old woman was admitted to our hospital for acute pancreatitis and cholangitis. Imaging examinations revealed a sessile nodule just above localized adenomyomatosis in the gallbladder fundus. Cholecystectomy with gallbladder bed resection was performed under the diagnosis of gallbladder carcinoma. Histopathologically, the sessile nodule was focal tubular adenocarcinoma in tubular adenoma of the pyloric gland type with no invasion, and the adenoma extended into a Rokitansky-Aschoff sinus in the localized adenomyomatosis. Neoplastic cells had mucus in the cellular cytoplasm. There was no strong evidence that suggested a relationship between carcinoma and adenomyomatosis. Acute pancreatitis and cholangitis may have occurred due to the passage of a neoplastic tissue fragment through the papilla, because there was no evidence of stone, bleeding, and mucus with high viscosity in the preoperative imaging examinations and the resected specimen.
