2021 Volume 63 Issue 7 Pages 1344-1350
Today, endocytoscopy, which has been called supermagnifying endoscopy, enables the endoscopic observation of crypts and nuclei through about 520-times magnification. Here we compared endocytoscopic images with histological findings and magnifying endoscopic findings using narrow band imaging and pit pattern. We enrolled 188 patients who underwent endoscopic or surgical resection after examination with endocytoscopy from December 2017 to September 2019. Endocytoscopic images were classified into 5 types based on the EC classification, and the endocytoscopic images in each type of EC classification were retrospectively compared with the histological findings of the resected specimens. EC 1b was mostly composed of serrated lesions (61.5％). EC 2 was mostly composed of adenomas or intramucosal cancers (60.2％ and 27.1％), and small numbers of submucosal invasive cancers and serrated lesions were also included (5.1％ and 4.2％). EC 3a was composed of intramucosal cancers and submucosal invasive cancers (33.3％ and 66.7％), and type EC 3b included only deeply submucosal invasive cancers (100％). The sensitivity of each classification except for EC 2 was not sufficient, but the specificity and the accuracy of each classification were acceptable. It is concluded that endocytoscopy is a useful modality for predicting the pathological findings.
