VISUALIZATION OF BOTH THE SMALL INTESTINE AND COLON USING A SECOND-GENERATION COLON CAPSULE ENDOSCOPY WITH AN ADAPTIVE FRAME RATE

Abstract

Second-generation colon capsule endoscopy (CCE-2), PillCam^TM COLON 2, is useful not only for detecting colorectal polyps but also for evaluating vascular lesions and inflammatory lesions, such as ulcers and erosions. CCE-2 enables observation of the entire gastrointestinal tract using an adaptive frame rate (AFR) throughout the examination. Manual setting up of an AFR at the start of the examination allows the observation of small intestinal lesions and colonic lesions with sufficient bowel preparation. Further, it is possible to measure the gastric, small intestinal, and colonic transit times. The manual setup method is also effective for avoiding problems associated with the delay in automatic startup of the AFR. Pan-enteric visualization is useful for evaluating many diseases, such as inflammatory bowel diseases other than Crohnʼs disease, gastrointestinal polyposis, intestinal infections, vasculitis, graft-versus-host disease (GVHD) and nonsteroidal anti-inflammatory drug (NSAID)-induced mucosal injury. For patients with Crohnʼs disease, it is hoped that the pan-enteric PillCam^TM Crohnʼs system will be approved in Japan in the future, as in the Western countries. Herein, we describe our clinical experience with a method to visualize both the small intestine and colon using an AFR.