抄録
Acute gastroduodenal ulcer found in cerebral damage, known as Cushing's ulcer, is one of the important prognostic complications, because gastrointestinal bleeding is frequently occurred. However, there are few reports on gastrointestinal complications in head injury. The authors studied on factors affecting gastrointestinal bleeding in 433 patients with head injury admitted to Osaka University Hospital from 1967 to 1973. The results are as follows: 1. Gastrointestinal bleeding was occurred in 72 of 433 patients with head injury (17%). 2. Gastrointestinal bleeding was related to the severity and type of head injury, the shock state, the oxygen concentration in arterial blood and the administration of glucocorticoid. 3. Gastrointestinal bleeding was occurred within two days after the trauma in 28 of 72 patients (39%), and within one week in 80%. 4. There was a definite relationship between the degree of gastrointestinal bleeding and the severity of head injury. All of nine patients with massive hemorrhage, who required blood transfusion over 1000ml, belonged to the severest head injury group, and were complicated with sepsis, shock or uremic state. 5. In 64 cases gastrointestinal bleeding could be controlled by conventional medical treatment. In the remaining eight cases, only one patient with duodenal ulcer was survived by emergency operation.