Abstract
We report two cases of angina pectoris having appeared after the endoscopic resection of the gastric mucosa (ER). The first case is a 80-year-old man, who was performed ER for an early gastric cancer. He complained of chest pain 4 days after ER, and the chest pain was relieved by sublingual administration of nitroglycerin tablet. Standard deviation of all sinus RR intervals over 24 hours, which is thought to show the state of the cardiac autonomic nervous activity, decreased after ER. The second case is a 58-year-old man, who had a non-obstructive hypertrophic cardiomyopathy, was performed ER for gastric adenoma. Chest pain appeared 4 days after the ER and it was relieved by sublingual treatment of nitroglycerin. Standard deviation of all sinus RR intervals over 24 hours decreased, and both spectral analysis and circulating levels of free norepinephrine showed that the sympathetic nervous activity seemes to be activated by the treatment of ER, which might cause vasospastic angina pectoris particularly in the patients with cardiac diseases.
