Continuous Local Antibiotics Perfusion (CLAP) for Periprosthetic joint infection of the hip: A case report

Abstract

Periprosthetic joint infection (PJI) of the hip is difficult to treat due to biofilm formation around the implant. Systemic administration of antibiotics is known to be ineffective against biofilms due to poor penetration into poorly vascularized tissues. The goal of PJI treatment is to achieve a therapeutic infection while retaining the implant. Our proposal, continuous local antibiotic perfusion (CLAP), delivers sufficient antibiotics locally and continuously to sites of bone and soft tissue infection, including around implants in the hip joint via a needle as intramedullary antibiotic perfusion. It is a delivery system that delivers to the soft tissue with dual antibiotic perfusion. Lumen hypodermic tubing as intra-soft tissue perfusion. We report a late chronic periprosthetic joint infection of the hip using CLAP treatment with implant preservation.