Genes & Genetic Systems
Online ISSN : 1880-5779
Print ISSN : 1341-7568
ISSN-L : 1341-7568
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Effect of dominance on heterozygosity and the fixation probability in a subdivided population
Jo NishinoFumio Tajima
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2004 年 79 巻 1 号 p. 41-48

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Under the assumptions of a subdivided population and the presence of dominance for fitness, the expected sum of heterozygosity in the total population during the lifetime of mutant was investigated. It was shown analytically and by computer simulations that in the island model the effect of dominance on the expected sum of heterozygosity decreases as the migration rate decreases and is lost almost completely when the migration rate is very low. In addition to the expected sum of heterozygosity, the fixation probability of mutant was also investigated. The effect of dominance on the fixation probability also decreases as the migration rate decreases but is not completely lost when the migration rate is very low.
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© 2004 by The Genetics Society of Japan
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