Genome Informatics
Online ISSN : 2185-842X
Print ISSN : 0919-9454
ISSN-L : 0919-9454
An Extension and Novel Solution to the (l, d)-Motif Challenge Problem
Mark P StyczynskiIsidore RigoutsosKyle L JensenGregory N Stephanopoulos
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ジャーナル フリー

2004 年 15 巻 2 号 p. 63-71

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抄録
The (l, d)-motif challenge problem, as introduced by Pevzner and Sze [12], is a mathematical abstraction of the DNA functional site discovery task. Here we expand the (l, d)-motif problem to more accurately model this task and present a novel algorithm to solve this extended problem. This algorithm is guaranteed to find all (l, d)-motifs in a set of input sequences with unbounded support and length. We demonstrate the performance of the algorithm on publicly available datasets and show that the algorithm deterministically enumerates the optimal motifs.
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© Japanese Society for Bioinformatics
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