抄録
D. Gohsh of National Center for Biotechnology Information (NCBI), National Library of Medicine, National Institute of Health originally maintained ‘TFD (Transcription Fac-tor Database)’ from 1990. As NCBI stopped its maintenance since 1993, we started a new database, TFDB (Transcription Factor Data Base), to take over some parts of the database focusing to the DNA binding sequence data. To update the database with recent data, we developed system which search literature database exhaustively and extract re-lated information from the abstracts of collectedarticles. We also developed mail server to search target sequence of transcription factor using this database.