2020 年 7 巻 2 号 p. 196-203
Subjective: Since the skin is constantly exposed to the external environment, it is susceptible to environmental factors. This may cause morphological changes due to skin aging, and the apparent age may occasionally exceed the chronological age. In the glycation reaction, a risk factor of skin aging, abnormal crosslinks are formed in collagen and elastin in the dermis, resulting in reduction of flexibility and elasticity. It is useful to impart an anti-glycation effect to cosmetics from the viewpoint of preventing skin aging. In this study, to develop a cosmetic material targeting inhibition of glycation reactions, we examined the approach by ume (Prunus mume), which is generally used in foods and health foods. Methods: The test samples were prepared by extracting from each site including the shoots (young branches), flowers, branches, leaves, bark, and roots of Ume, the two varieties of Bungo and Shirakaga. Using this extracts, we verified the activities of SOD (superoxide dismutase)-like action, DPPH (2,2-Diphenyl-1-picrylhydrazyl) radical scavenging, elastase inhibition, and Maillard reaction crosslinking inhibition. Results: The effects of elastase inhibiting, anti-oxidant, and anti-glycation were observed in ume root extracts of both varieties; Bungo and Shirakaga. Conclusion: It has been found that the beneficial effect is on the plum root, of which extracts can be expected to be a useful raw material for preventing skin aging.
