1982 Volume 22 Issue 4 Pages 467-474
A 64 year-old man was admitted with a small abnormal mass shadow located in the left peripheral lung field. Transbronchial lung biopsy was done and the pathological diagnosis was bronchioloalveolar cell carcinoma, “goblet type”.
Left upper lobectomy was performed. Sarcoid-like lesions were found in regional lymphnodes. Histologically, the tumor cells appeared to extend along alveolar walls. The cells were high columnar to cuboidar shaped. Marked mucin secretion was found in the alveoli.
Electron microscopic findings: There were numerous apical mucus granules in the tumor cell cytoplasms. The cell-to-cell attatchments were formed by tight junctions, desmosomes and interdigitations.
Scanning electron microscopic findings: Tumor cells proliferated along the alveolar walls and passed through Kohn's pore.