Abstract
This paper presents the effects of hyaluronidase on rat leprosy.
1) Rat leprosy bacilli were injected intracutaneously into white rats as follows: a) together with hyaluronidase; b) injected at a site into which hyaluronidase was injected one hour before; c) bacilli injected alone as controls. The effects of hyaluronidase were not found on this experiment.
2) Rat leprosy bacilli were injected subcutaneously into white rats, alone and with hyaluronidase.
Hyaluronidase accelerated the development of granuloma on subcutaneous inoculation.
