ON THE ABSORPTION OF SULFONES TO RED BLOOD CELLS

Abstract

In vitro expertment on the absorption of sulfones, especially of promin and promizole, to red blood cells supplied us following results:
(1) Both promin and promizole are absorbed to red blood cells, and the ratio is larger with promizole than with promin. And the absorption occurs according to Freundlich's absorption isoterm.
(2) The absorption of these sulfones is inhibited by the presence of blood plasma.
(3) Both drugs are combined well with serum albumin, but not at all with serum euglobulin. The mesurement with Tiselis' electrophoresis showed that promizole is stronger in the combination than promin.