抄録
1) I employed Promin, mixed with Strychinine Nitrate, and examined the absorption of this drug through the skin by means of estimation of the dead time of mice. According to the results of the experiments Promin is the superior drug as an ointment.
2) I examined the absorption of Promin through the skin of rabbits, Promin in urine showed the highest excretion at the 6th hour.
I compared Promin which is used through the skin and that used by intraveneous injection; the result reveals that the former showed 1.3-6.1% of the latter in urine concentration.
3) Further I examined the influence of Promin, through the skin of rabbits, on the quantity of Ca in blood and urine, and Fe in blood. I recognized that the quantity of them increased slightly.
