抄録
It is generally believed that there is a definite bacteriological relation between the quantity of bacilli and the degree of the morbid change caused by them.
The author made an emulsion of twenty times of leproma and vaccinated its 0, 5-1, 0 c.c. In the case of observations on the influence of gynocardic oil and other medicals or nutriments upon the rats morbid change, we noticed that the exessive quantity of the vaccinated bacilli may cause the severe acute morbid change through which the result of a second influence may be put in confusion to he judged. Hence taking the above mentioned emulsion as the original, we diluted it by 10-100-1.000-10.000 times and vaccinated 0, 5 cc of each liquid on four white rats, which we billed after four months and we compared their morbid changes.
As for the result of the experiments, a severe morbid change was produced by the original liquid or the liquid diluted by 10 times, but a slight change by the liquid diluted by 100 times or more. It is very into*resting that even the liquid diluted by 10.000 times can produce a morbid change. Accordingly as the smallest vaccinal quantity of rat's leprous bacilli which can produce a morbid change without failure, we are used to vaccinate 0, 5 cc of the liquid which was made by diluting the original emulsion by 100 times
