Hosokawa Powder Technology Foundation ANNUAL REPORT
Online ISSN : 2189-4663
ISSN-L : 2189-4663
Research Grant Report
Mechano-Processing of Hollow and/or Composite Bio-Materials
Takeo HyodoMakoto EgashiraYasuhiro ShimizuKazutaka Kamitani
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RESEARCH REPORT / TECHNICAL REPORT FREE ACCESS

2007 Volume 15 Pages 77-81

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Abstract

Core/shell microspheres (core : polymethylmethacrylate (PMMA, ca. 90 μm in diameter), shell : hydroxyapatite (HA) mixed with a small amount of fumed silica) could be prepared by employing a mechanofusion system. The shell thickness and surface roughness of hollow microspheres, which were obtained by heat-treatment (1200℃ in air) of the core/shell microspheres, could be controlled by adjusting the mixing ratio of HA-based powders and PMMA microspheres in the raw materials. A mixture of the core/shell composites and a HA sol was subjected to firing at 1200℃ in air to prepare porous HA bodies. The amount of protein adsorbed increased with an increase in pore volume of the porous HA bodies.

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