Recently, masks have become a must-have item due to the COVID-19 problem. The eye area not covered by mask, especially the eyelashes, has become an important part of a person’s first impression. In recent years, human stem cell culture supernatant has been attracting attention as a new cosmetic ingredient born from regenerative medicine technology for the purpose of growing eyelashes thicker and longer. The various growth factors and cytokines contained in the supernatant powerfully activate cells involved in hair growth, producing a strong hair-growing effect. However, due to the large molecular size of the supernatant contents, it has been difficult to penetrate the supernatant contents to the cells deep inside the pores, the target site for eyelash hair growth. In this paper, we focus on this human stem cell culture supernatant and report on its eyelash growth effect by combining it with PLGA nanoparticles’ DDS (Drug Delivery System) technology we have built which can deliver supernatant contents to the target site well.

Today, the hair-growth agent market continues to expand as the range of user base broadens. High efficacy that brings noticeable changes in hair is the key point for consumers to select hair restoration products. To achieve that, we examined to maximize the performance of our products by picking out effective materials and delivering them to pores. We tested ingredients through cell experiments and improved their functionality with our PLGA nanoparticles (PLGA NP) technology, which excels in pore penetration and durability.

The development of energy-efficient products is an essential responsibility of companies manufacturing and selling industrial equipment. This paper reports on the energy-efficient hot air jet mill and the ACM-F, the latest model of the impact pulverizer ACM with built-in classifier, which was developed considering energy savings. It also presents an overview of the HOSOKAWA GEN4 RM, a remote monitoring and data collection system that was launched as a first product towards improving the efficiency of the entire plant.

The IoT has a SoS nature that creates additional new value by connecting with the IoT used in other equipment, resulting in a ‘connected world’. In factories handling powders in the connected world, online and in-line monitoring of the condition of powders and equipment, as well as their condition, is essential for quality inspections to check whether products meet shipping standards, or for both minimizing energy consumption and maximizing throughput during the production of products and raw materials, and for systems to analyze big data are essential. However, there are currently a number of problems that stand in the way of bringing measuring equipment online. This paper addresses these issues in order to provide seeds for powder engineering, and also introduces the remote monitoring system that is part of the IoT integration framework HOSOKAWA GEN4 for powder processes.

The necessity of global warming countermeasures is recognized worldwide, and various efforts are being made in Japan, such as reducing CO₂ emissions. In particular, factories emit a large amount of CO₂, which has a large impact on global warming. Therefore, we would like to introduce our DRYMEISTER^® (hereinafter referred to as DMR) superheated steam closed circuit system as a drying technology that can save energy and reduce CO₂ in the drying process of factory equipment and is a countermeasure against global warming. This system is characterized by the reuse of hot air that has been discharged into the atmosphere at a relatively high temperature after being used for drying.