Hypertension Research
Online ISSN : 1348-4214
Print ISSN : 0916-9636
ISSN-L : 0916-9636
The Relationship of Dietary Factors to Cardiovascular Diseases among Japanese in Okinawa and Japanese Immigrants, Originally from Okinawa, in Brazil
Shunsaku MizushimaEmilio Hideyuki MoriguchiYasuhiko NakadaMaria D. Gonzáles BioscaYasuo NaraKeiji MurakamiRyoichi HorieYukio MoriguchiGoro MimuraYukio Yamori
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1992 年 15 巻 1 号 p. 45-55

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To investigate the relationship of dietary factors to cardiovascular diseases, we conducted a study of 234 middle-aged Japanese men and women in Okinawa (JJ), and 160 Japanese immigrants of similar age, originally from Okinawa, in Brazil (JB). JB showed double the prevalence (%) of ST-T changes in the electrocardiogram (ECG) (JJ: M3.4, F4.4, JB: M8.3, F10.1) and of hypertension (HT) (JJ: M15.9, F18.4; JB: M32.8, F36.4, p<0.05) when this was assessed on BP≥160/95 and/or the taking of antihypertensive medication; however the mean level of blood pressure did not differ. A gradient in the rate of HT in men and of ECG ST-T changes in both sexes was observed from JJ to JB of first-generation and to JB of second-generation. JB had much higher body mass index (kg/m2) (JJ: M24.8±0.3, F24.8± 0.4; JB:M26.2±0.4, F26.5±0.4, p<0.01) in both sexes, and an 8-fold higher rate of oral contraceptive usage (p<0.001). Total cholesterol level showed no significant difference between JJ and JB. 24-hour urinary taurine excretion in both sexes and plasma phospholipid n-3 fatty acid level in men were significantly higher in JJ than in JB. The dietary pattern in Japanese immigrants in Brazil, characterized by low fish and large meat intake, is possibly responsible for the higher risk of HT and ECG ST-T changes, indicating the importance of dietary rather than genetic factors. (Hypertens Res 1992; 15: 45-55)

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