2012 年 132 巻 8 号 p. 616-622
We previously measured for healthy subjects and patients who require hemodialysis the complex relative permittivity (εr´-jεr´´) of whole blood, and found that εr´-axis intercept εrt´ of straight line approximation to the Cole-Cole plots at frequencies from 200 MHz to 1GHz is significantly different with a level of less than 1% among its averaged values for healthy subjects and patients before and after dialysis, though any correlations between εrt´ and blood urea nitrogen (BUN) and creatinine being used as main indices for hemodialysis evaluation have not so far been clarified.
In this study, to make correlation analyses between the intercept εrt´ and blood biochemical components for nine patients before and after hemodialysis, we measured six kinds of their blood components including BUN and creatinine, and calculated their Pearson product-moment correlation coefficients for εrt´ along with significant probability P based on a t-test. It should be noted that P is a reference probability to determine whether or not a null hypothesis can be rejected, and that the P value of 0.05 is commonly used as a significance level for statistical test. As a result, we found that a strong correlation with P < 0.05 is observed between εrt´ and albumin, while there are not always significant correlations with P > 0.05 between εrt´ and other blood components including BUN and creatinine. Although albumin is not used as an index for hemodialysis efficiency, it can reflect water amount in blood vessels and liver operation. This finding implies that εrt´ could be used as an index for evaluating blood viscosity and liver function.
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