2019 年 139 巻 9 号 p. 360-366
Much progress in the field of organic nanotechnology and biomolecular electronics for environmental preservation will be expected in 21st century. A bio-device using information transfer-conversion system of the creature is a biosensor. By quick sensing the invasion of the pathogen from the outside, possessing a role which transmits the information to a cell is an immunosensor. The estimation of low density lipoprotein (LDL) cholesterol is important parameters for clinical diagnostics. We have fabricated an immunosensor based on apolipoprotein B (AAB) functionalized carbon nanotubes (CNT) for LDL detection using electrochemical measurement methods. Our proposed immunosensor is on the basis of antibody (AAB)-antigen (LDL) interaction. This immunosensor is found to be selective for LDL and exhibits a wide detection range of LDL shows higher sensitivity and first response. Higher stability of this proposed immunosensor has been observed due to covalent functionalization of AAB on functionalized CNT nanocomposite surface. The most familiar area biotechnology which is based on amicable use of unique biological function towards betterment of human life and environmental conservation cannot deny the important role played by the ions. "Solion" is an electronic circuit device using migration of ions in electrolytic solution.
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