Potential of Deeper Brain Stimulation using Magnetic Fields

Abstract

This paper reviews non-invasive brain stimulation using electromagnetic fields, particularly for the treatment of mental disorders such as depression. Transcranial magnetic stimulation (TMS) and temporal interference (TI) stimulation could be alternatives to conventional electroconvulsive therapy. A recent study showed that the design of TMS coils has been optimized for deeper brain penetration while maintaining focality. In addition, TI stimulation has the ability to selectively target deep brain regions. These findings contribute to the development of effective, non-invasive neuromodulation therapies that may improve outcomes for drug-resistant patients.