A MEG/EEG Hybrid Method for Source Localization of a Dipole with Radial Component

Abstract

The location of a current dipole in human brain is obtained with good accuracy by using MEG. However, it is difficult to estimate a radial component of the dipole by MEG, because a shape of human head resembles to a sphere. We developed a novel MEG/EEG hybrid method based on the consideration of merits of MEG and EEG to estimate a current dipole with radial component. A simulation investigated the performance of this method. It was shown that the accuracy of the source localization by this method was better than the accuracy of the estimation by other methods such as usual MEG/EEG hybrid method. This method was also applied to the real MEG and EEG evoked by median nerve stimulation.