Fabrication of Self-assembled Monolayer/AgCl Mixed Surface and It's Electrochemical Properties

Abstract

There is increasing interest on solid-state biosensors due to potential advantages such as small size, low-cost, high density integration for point of care testing and next-generation drug discovery. In many cases, a gold electrode is used as a sensing surface on which specific biomolecule recognition events take place. However, gold is not always the best material for potentiometric measurement since the surface of gold electrode is polarized in aqueous solution, and there is room for improvement in stability of interface potential at the gold electrode surface. In this paper, we fabricated and characterized the mixed surface of self-assembled monolayer of alkanethiol and silver chloride to realize both stable interface potential and immobilization of biomolecules.