Abstract
Despite increasing interest in remote lifestyle modification, evidence regarding the effectiveness of digital interventions in improving coronary risk factors remains limited. This study presents preliminary findings on a web-app-based remote lifestyle modification program including exercise, diet, and education aimed at managing coronary risk factors in patients following percutaneous coronary intervention (PCI). This single-arm interventional study enrolled 30 patients who had undergone PCI. The intervention protocol included a 5-day comprehensive lifestyle assessment, followed by a 12-week lifestyle modification program delivered through a web-based application. Participants engaged in home-based exercise training, dietary monitoring, and health assessments via the app. Instructors supervised their progress, provided feedback, and facilitated goal-setting for subsequent 2-week periods through a chat-based platform. A total of 24 participants (80%) successfully completed the program, with no adverse events or emergency medical visits related to the intervention. Significant improvements were observed in several clinical parameters, including reductions in systolic blood pressure (P = 0.043), low-density lipoprotein cholesterol (P < 0.001), high-density lipoprotein cholesterol (HDL-C) (P < 0.001), non-HDL-C (P < 0.001), and HbA1c (P = 0.038). There were significant increases in peak VO2 (P < 0.001), moderate-to-vigorous physical activity (P = 0.012), and the mental component summary score of the SF-36 questionnaire (P = 0.003). Among 14 participants with elevated baseline body mass index, significant weight reduction was achieved (P = 0.008). The web app-based lifestyle modification program was feasible and safely implemented in patients after PCI. The efficacy and cost-effectiveness of asynchronous, technology-supported interventions for the comprehensive management of coronary heart disease should be further investigated in future randomized controlled trials.
