抄録
Experiments were carried out to study whether thiamine deficiency is connected with alcoholic heart disease or not.
Thiamine deficient rats were orally given shochu, whisky and 40% ethanol either until the last stage or for 10 weeks through a stomach tube.General symptoms, electrocardiographic abnormalities, and cardiac histological and electron microscopical changes in the alcohol administered groups were less severe than those in the non-administered group. That is the alcohol lessened thiamine deficient cardiac lesions.
From the above, it is assumed that alcoholic heart disease is of essentially different nature from thiamine deficient cardiac lesions. And discussions were given on the mechanism.
