2023 年 4 巻 4 号 p. 133-138
Introduction: Wound odors are caused by bacteria and necrotic tissue, which severely degrade a patient’s quality of life. However, the management of wound odors is difficult for physicians. Dialkylcarbamoyl chloride-coated dressings can reduce bacterial load in wounds through hydrophobic interactions. In this study, we evaluated whether dialkylcarbamoyl chloride-coated dressings reduced wound odor by reducing bacterial load.
Materials and methods: The target population was composed of patients with wounds and those who met the criteria for the use of dialkylcarbamoyl chloride-coated dressings. The dressing and gauze were changed every 24 hours. Before and 7 days after the use of the dialkylcarbamoyl chloride-coated dressing, gauze soaked in exudate was collected, then the odor was subjectively rated using a six-stage odor intensity scale, and objectively assessed using a handheld odor meter. A swab culture test of the wounds was performed simultaneously and the bacterial loads were compared.
Results: Dialkylcarbamoyl chloride-coated dressing use tended to reduce wound odor as evaluated by the six-stage odor intensity scale (2.0 ± 1.6 vs. 3.7 ± 1.2, P = 0.005) and the handheld odor meter (334.7 ± 409.4 vs. 754.8 ± 352.0, P = 0.003). However, there was no difference in bacterial load (7.7 × 106 ± 1.2 × 107 vs. 2.8 × 107 ± 6.0 × 107, P = 0.21).
Conclusion: This study demonstrated that dialkylcarbamoyl chloride-coated dressings reduce wound odor in subjective and objective assessments. These findings may provide a new option for managing odorous wounds.
