Pentamidine Administered Subcutaneously in the Abdomen Resulted in Fat Degeneration Without Skin Ulceration

A Case Report

抄録

Pentamidine is one of the oldest drugs currently used to treat Pneumocystis carinii pneumonia. Reports of complications from administration include skin side effects, such as skin necrosis, sterile abscesses, and ulceration at the injection site when administered intramuscularly, and urticaria formation near the site of injection when administered intravenously. We herein report an unintended subcutaneous injection of pentamidine in the abdomen of a patient with asthma instead of omalizumab, which resulted in soft tissue depressions and adipose tissue necrosis secondary to dermatitis without skin ulceration. The dermatitis improved with the use of a topical steroid ointment, but the depressions persisted; therefore, scar resection and liposuction were performed to improve the morphology of the abdomen.