COPROPORPHYRINS IN LEAD AND MERCURY WORKERS
1964 Volume 2 Issue 3-4 Pages 162-171
Details
1964 Volume 2 Issue 3-4 Pages 162-171
Coproporphyrin determination by the Askevold method is simple, easy and inexpensive.Coproporphyrin determination may be better than urinary lead analyses when well equipped laboratories and technicians with experienced training are not available, especially in small industries or perhaps in developing countries. For the screening periodic examination of lead workers to obtain information of lead exposure, and to prevent lead poisoning of those workers, it was demonstrated in the present study that one might skip urinary lead analyses which should be carried out for suspected cases. Because urinary coproporphyrin increase nicely paralleled that of lead, and in the copro-porphyrin determination there could be considered no such fear of contamination or analytical errors which might yield in the determination of urinary lead.
According to the combined observations of the present as well as the previous study, the threshold limit value of lead in air was assumed to be around 0.08 to 0.12mg/m3 for coproporphyrin increase.
In mercury absorption coproporphyrin was found to increase tosome extent, and mercury exposure as a group will be detected by plotting data on paper of logarithmic normal probability, provided a standard distribution curve obtained from normal subjects.
