Scintigraphic Evaluation of Cardiac Metabolism in Multicentric Castleman’s Disease

Abstract

A 72-year-old woman had insidious onset of heart failure, and was diagnosed as multicentric Castleman’s disease. She underwent myocardial imaging with technetium-99m tetrofosmin, I-123 beta-methyl-iodophenyl pentadecanoic acid (BMIPP). Technetium-99m tetrofosmin studies showed almost normal uptake of the left ventricular myocardium indicating normal myocardial perfusion. I-123 BMIPP showed reduced uptake in the apical segment of the myocardium, indicating regional fatty acid metabolic abnormalities.