Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
Respiratory Diseases
Successful Treatment of Hypersensitivity Pneumonitis Caused by Grifola frondosa (Maitake) Mushroom Using a HFA-BDP Extra-fine Aerosol
Hiroshi TANAKAKazunori TSUNEMATSUNaohito NAKAMURAKazuhiko SUZUKINobuyuki TANAKAIsao TAKEYAToyohiro SAIKAIShosaku ABE
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JOURNALS OPEN ACCESS

2004 Volume 43 Issue 8 Pages 737-740

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Abstract

We successfully treated a patient with occupational hypersensitivity pneumonitis (HP) caused by Grifola frondosa (Maitake) mushroom spore with an extra-fine aerosol corticosteroid; beclomethasone dipropionate (BDP) dissolved in hydrofluoroalkane-134a (HFA). A 49-year-old woman developed respiratory symptoms 3 months after beginning work on a mushroom farm. She was diagnosed as HP based on radiological and serological findings. Oral prednisolone therapy improved her HP and she returned to the same farm. Her HP relapsed after 5 months, and daily 400 μg of HFA-BDP was administered with gradual improvement. An extra-fine particle inhaled corticosteroid might reach appropriate alveoli to be effective therapy for mild HP.

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© 2004 by The Japanese Society of Internal Medicine
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