Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Wernicke's Encephalopathy that Developed during the Introduction Period of Peritoneal Dialysis
Yuko NakashimaKenji ItoHitoshi NakashimaAki ShirakawaYasuhiro AbeSatoru OgaharaYoshie SasatomiTomoe YasunagaMasakazu IfukuJun TsugawaYoshio TsuboiTakao Saito
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2013 Volume 52 Issue 18 Pages 2093-2097

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Abstract

A 43-year-old man was admitted with end-stage renal disease caused by IgA nephropathy, and was treated with maintenance peritoneal dialysis. The patient developed general fatigue and appetite loss, and his symptoms were gradually aggravated by depression. After approximately 2 months on dialysis, the patient presented with altered consciousness and ophthalmoplegia. Wernicke's encephalopathy was diagnosed based on the presence of classic symptoms and the findings on magnetic resonance imaging. Thiamine replacement therapy was immediately initiated. The patient recovered from most of his neurological symptoms; however, the sequela of Korsakoff syndrome remained. A marginal thiamine deficiency in combination with predisposing factors must be considered when treating dialysis patients.

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© 2013 by The Japanese Society of Internal Medicine
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