Three Patients with Familial Mediterranean Fever: A Possible Underdiagnosed Entity in Japan

Kei Yokota; Masamichi Fukuda; Kiyoshi Migita; Eiichiro Tanaka; Tadashi Okamoto; Kenjiro Kimura

doi:10.2169/internalmedicine.53.2580

CASE REPORTS

Three Patients with Familial Mediterranean Fever: A Possible Underdiagnosed Entity in Japan

Kei Yokota, Masamichi Fukuda, Kiyoshi Migita, Eiichiro Tanaka, Tadashi Okamoto, Kenjiro Kimura

Author information

Keywords: familial Mediterranean fever, elderly, IgA nephropathy, MEFV, colchicine

JOURNAL OPEN ACCESS

2014 Volume 53 Issue 17 Pages 2013-2016

DOI https://doi.org/10.2169/internalmedicine.53.2580

Details

Abstract

Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by periodic fever and serosal inflammation. FMF is mostly reported in the Mediterranean region and is considered to be rare in Japan with estimated 292 cases. We treated three unrelated FMF patients in one year in a city with 144,000 residents. Two of the three patients were over 70 years old. FMF may therefore be underdiagnosed in Japan.

Corresponding author

Register with J-STAGE for free!