Intracholecystic Papillary-tubular Neoplasm of the Gallbladder Presenting with Jaundice

Shinichi Hashimoto; Jun Horaguchi; Naotaka Fujita; Yutaka Noda; Go Kobayashi; Kei Ito; Shinsuke Koshida; Yoshihide Kanno; Takahisa Ogawa; Kaori Masu

doi:10.2169/internalmedicine.53.2778

CASE REPORTS

Intracholecystic Papillary-tubular Neoplasm of the Gallbladder Presenting with Jaundice

Shinichi Hashimoto, Jun Horaguchi, Naotaka Fujita, Yutaka Noda, Go Kobayashi, Kei Ito, Shinsuke Koshida, Yoshihide Kanno, Takahisa Ogawa, Kaori Masu

Author information

Shinichi Hashimoto
Department of Digestive and Lifestyle Related Disease, Health Research Course, Human and Environmental Sciences, Kagoshima University Graduate School of Medical and Dental Sciences, Japan
Department of Gastroenterology, Sendai City Medical Center, Japan
Jun Horaguchi
Department of Gastroenterology, Sendai City Medical Center, Japan
Naotaka Fujita
Department of Gastroenterology, Sendai City Medical Center, Japan
Yutaka Noda
Department of Gastroenterology, Sendai City Medical Center, Japan
Go Kobayashi
Department of Gastroenterology, Sendai City Medical Center, Japan
Kei Ito
Department of Gastroenterology, Sendai City Medical Center, Japan
Shinsuke Koshida
Department of Gastroenterology, Sendai City Medical Center, Japan
Yoshihide Kanno
Department of Gastroenterology, Sendai City Medical Center, Japan
Takahisa Ogawa
Department of Gastroenterology, Sendai City Medical Center, Japan
Kaori Masu
Department of Gastroenterology, Sendai City Medical Center, Japan

Keywords: intracholecystic papillary-tubular neoplasms, ICPN, gallbladder cancer, mucin-producing tumor, intraductal papillary neoplasm of the bile duct, IPNB

JOURNAL OPEN ACCESS

2014 Volume 53 Issue 20 Pages 2313-2317

DOI https://doi.org/10.2169/internalmedicine.53.2778

Details

Abstract

We herein report a case of intracholecystic papillary-tubular neoplasm (ICPN) of the gallbladder in which jaundice developed. A 58-year-old woman with jaundice was referred to our hospital. Computed tomography revealed a papillary tumor in the body of the gallbladder protruding into the bile duct. A transpapillary biopsy of the bile duct verified adenocarcinoma, and pancreatoduodenectomy with extended cholecystectomy was performed. The tumor spread macroscopically from the gallbladder body to the cystic duct, thus forming a polypoid mass protruding into the bile duct. This is a rare case of invasive carcinoma from ICPN leading to mechanical obstruction of the bile duct.

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