Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Miller Fisher Syndrome Following Vaccination against SARS-CoV-2
Makoto YamakawaKeiichi NakaharaToshihito NakanishiToshiya NomuraMitsuharu Ueda
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JOURNAL OPEN ACCESS

2022 Volume 61 Issue 7 Pages 1067-1069

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Abstract

After BNT162b2 messenger ribonucleic acid (mRNA) coronavirus disease 2019 (COVID-19) vaccination, a 30-year-old man developed bilateral lateral gaze palsy, diplopia, absent tendon reflexes, and ataxic gait. Serum anti-GQ1b and anti-GT1a immunoglobulin G (IgG) antibodies were strongly positive. Based on those findings, he was diagnosed with Miller Fisher syndrome (MFS). Intravenous immunoglobulin therapy was administered, and his symptoms fully recovered within approximately 3 months. To the best of our knowledge, this is the first report to describe the development of MFS after COVID-19 mRNA vaccination.

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© 2022 by The Japanese Society of Internal Medicine
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