Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
An Unusual Case of Brucellosis in Japan: Difficulties in the Differential Diagnosis from Pulmonary Tuberculosis
Hiroki TAKAHASHIShintaroh TANAKAKazuhiro YOSHIDAHideaki HOSHINOHiroko SASAKIKohji TAKAHASHIKohichi KIMURANobuhiro FUJIIHiromichi KIMURAMichio MORIShosaku ABE
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1996 Volume 35 Issue 4 Pages 310-314

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Abstract

Human brucellosis is an imported zoonosis extremely uncommon in Japan. Brucellosis was found in a 38-year-old surgeon who had never been abroad; he developed intrapulmonary infiltrates and pleural thickening indistinguishable from pulmonary tuberculosis. Despite extensive antibiotic therapy for tuberculosis he developed systemic serositis. A culture of resected lung tissues grew CO2-required coccobacilli. Polymerase chain reaction test using a specific primer pair for Brucella abortus revealed that the isolated pathogen is highly homologous to B. abortus. We emphasize that undetermined cases of human brucellosis may be present in Japan.
(Internal Medicine 35: 310-314, 1996)

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© The Japanese Society of Internal Medicine
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