Peripheral Arterial Occlusive Disease in Kimura's Disease: A Case Report and Literature Reviews

Abstract

Kimura's disease is a lymphoproliferative disorder characterized by eosinophilic infiltration. Although it rarely causes peripheral arterial occlusive disease, its mechanism remains unclear. A 43-year-old man with a seven-year history of Kimura's disease, initially presenting with a cervical mass and treated with prednisolone, developed an ulcerative lesion from the right thumb to the middle finger. Ultrasonography revealed bilateral radial artery dilation and thrombosis. After he was diagnosed with Kimura's disease-associated vasculitis, he was treated with prostaglandin E1, warfarin, and cilostazol. Because of persistent symptoms, angioplasty was performed on the occluded radial artery. The patient's symptoms improved on the first postoperative day, with no re-occlusion observed after 2 years. Percutaneous transluminal angioplasty has been demonstrated as effective for early symptomatic relief in Kimura's disease.