Interventional Radiology
Online ISSN : 2432-0935
Current issue
Displaying 1-50 of 81 articles from this issue
TECHNICAL NOTE
  • Shoma Nagata, Hiroshi Kawada, Mizuki Hirata, Shigeru Kiyama, Yoshifumi ...
    Article type: TECHNICAL NOTE
    2025Volume 10 Pages e2025-0057
    Published: December 29, 2025
    Released on J-STAGE: December 29, 2025
    JOURNAL OPEN ACCESS

    Purpose: To retrospectively evaluate the safety and efficacy of direct oral anticoagulant therapy for fibrin sheath-induced central venous port system dysfunction.

    Material and Methods: Between May 2023 and February 2024, patients who underwent direct oral anticoagulant therapy for fibrin sheath-induced central venous port system dysfunction were included. The clinical effectiveness, flow confirmation study, central venous port function, and adverse events according to the Common Terminology Criteria for Adverse Events classification were retrospectively reviewed.

    Results: Nine patients were included in the study. The catheter types were open-ended (n = 8) and Groshong (n = 1). All patients had difficulty with aspiration, and one exhibited injection resistance. All patients received edoxaban as direct oral anticoagulant, at doses of 30 mg (n = 3) or 60 mg (n = 6) based on their body weights. After direct oral anticoagulant administration, complete fibrin sheath resolution was confirmed by a flow confirmation study in all cases, with a mean duration of 29 ± 21 days. Concurrently, the central venous port system dysfunction was restored in eight cases. In the remaining one case, direct oral anticoagulant administration was suspended on day 26 due to grade 1 epistaxis; therefore, central venous port system dysfunction remained despite the disappearance of the fibrin sheath. Thus, the clinical success rate was 88.9% (8/9) and fibrin sheath disappearance rate was 100% (9/9), respectively. No grade 3 or higher adverse effect was observed. No recurrence of fibrin sheath-induced central venous port system dysfunction was observed during the mean follow-up period of 133 ± 98 days.

    Conclusions: Direct oral anticoagulant administration can be a potentially effective and safe strategy for managing fibrin sheath-induced central venous port system dysfunction formation.

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CASE REPORT
  • Kenji Takata, Toyohiko Sakai, Midori Ueda, Kiyotaka Takeuchi, Hideaki ...
    Article type: CASE REPORT
    2025Volume 10 Pages e2024-0059
    Published: December 29, 2025
    Released on J-STAGE: December 29, 2025
    JOURNAL OPEN ACCESS

    Portal vein stenting treats stenosis or thrombosis of the portal venous system with relatively high technical and clinical success rates. However, complications have been reported. We present a case of a 58-year-old woman with a history of pancreatic head cancer surgery who developed superior mesenteric vein occlusion owing to recurrent mesenteric lesions. Portal vein stenting was performed; however, it resulted in superior mesenteric artery occlusion, which caused extensive intestinal ischemia. Gas from the intestinal necrosis migrated into the superior mesenteric artery and superior mesenteric vein, and thrombotic occlusion of the portal vein stent was observed. This complication, which is characterized by superior mesenteric artery occlusion induced by portal vein stenting, is unique. Furthermore, this case highlights the need for a thorough preoperative evaluation and careful consideration to avoid such a rare but severe complication.

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  • Yamato Tsunoda, Hirotatsu Sato, Tetsuo Sonomura, Yuichi Miyake, Naoki ...
    Article type: CASE REPORT
    2025Volume 10 Pages e2025-0025
    Published: December 29, 2025
    Released on J-STAGE: December 29, 2025
    JOURNAL OPEN ACCESS

    A man in his 60s presented with severe epigastric pain. Abdominal computed tomography revealed an aneurysm of the right gastric artery, which branched from an aberrant gastroduodenal artery originating from the axis of the splenic artery. Other vascular anomalies included a left gastric artery arising directly from the aorta and several additional arterial variations. Computed tomography also revealed stenosis of the axes of the celiac artery and left gastric artery. The aneurysm was thought to be caused by the stenosis due to median arcuate ligament syndrome. Transcatheter arterial embolization was successfully performed. This case highlights that median arcuate ligament syndrome combined with vascular anomalies can alter hemodynamics and lead to the development of uncommon gastric artery aneurysms.

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ORIGINAL RESEARCH
  • Akira Morimoto, Midori Yamamura, Yuko Miki, Ichiro Fujiwara, Akira Yam ...
    Article type: ORIGINAL RESEARCH
    2025Volume 10 Pages e2025-0063
    Published: December 29, 2025
    Released on J-STAGE: December 29, 2025
    JOURNAL OPEN ACCESS

    Purpose: Percutaneous transluminal angioplasty for forearm arteriovenous fistula stenosis is frequently associated with significant pain, which may hinder patient cooperation. Ultrasound-guided cutaneous nerve blocks were evaluated as an alternative analgesic method for percutaneous transluminal angioplasty in forearm arteriovenous fistula, with the aim of reducing pain without motor paralysis or systemic complications.

    Material and Methods: This retrospective, single-center study included 77 patients who underwent percutaneous transluminal angioplasty for forearm arteriovenous fistula stenosis with ultrasound-guided cutaneous nerve block using lidocaine in October 2024. Target nerves included the lateral antebrachial cutaneous nerves, the superficial branch of the radial nerve, and/or the medial antebrachial cutaneous nerves. We retrospectively collected data on block time, percutaneous transluminal angioplasty duration, lidocaine volume, complications, presence or absence of postanesthetic motor paralysis, and analgesic efficacy. Analgesic efficacy was graded as excellent, good, or poor, with "poor" defined as pain necessitating supplemental local infiltration anesthesia for adequate relief.

    Results: The mean block preparation time was 2.1 ± 0.5 min, and the percutaneous transluminal angioplasty duration was 27.3 ± 9.2 min. The mean volume of 1% lidocaine used was 2.6 ± 1.1 mL. Minor hematomas were observed in eight cases. No patient experienced postanesthetic motor paralysis. Analgesia was rated excellent in 57.1% of patients and good in 29.9%, while poor analgesia occurred in only 12.9%. A superficial branch of the radial nerve block improved outcomes in distal forearm lesions.

    Conclusions: Ultrasound-guided cutaneous nerve blocks provide rapid, effective, and motor-sparing analgesia for percutaneous transluminal angioplasty of forearm arteriovenous fistula stenosis, making them suitable for outpatient use and warranting further prospective evaluation.

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  • Soichiro Okamoto, Yusuke Matsui, Koji Tomita, Kazuaki Munetomo, Noriyu ...
    Article type: ORIGINAL RESEARCH
    2025Volume 10 Pages e2025-0068
    Published: December 29, 2025
    Released on J-STAGE: December 29, 2025
    JOURNAL OPEN ACCESS

    Purpose: To evaluate the efficacy of needle tract sealing using normal saline instillation for decreasing the risk of pneumothorax after computed tomography-guided lung biopsy.

    Material and Methods: This retrospective, single-institution study included 391 computed tomography-guided lung biopsies performed by 12 operators between January 2022 and October 2024. After exclusion, 298 biopsies were analyzed by comparing the saline seal (n = 138) and control (n = 160) groups. A 17/18-gauge or 19/20-gauge coaxial biopsy system was used, and tract sealing was performed by instilling 1-5 mL of normal saline during the withdrawal of the introducer needle in the saline seal group; tract sealing was not performed in the control group. After 1:1 propensity score matching was performed to balance baseline characteristics, the incidences of pneumothorax and chest tube placement were compared between the two groups using Fisher's exact test.

    Results: After propensity score matching, 108 pairs (mean lesion size: 17 mm) were well balanced. The incidence of pneumothorax did not differ significantly between the control and saline seal groups (50.0% vs. 60.2%, respectively; p = 0.171). Similarly, the incidence of chest tube placement was not significantly different between the two groups (7.4% vs. 13.0%, respectively; p = 0.260).

    Conclusions: According to the propensity score-matched analysis, normal saline instillation for tract sealing did not significantly reduce the incidence of pneumothorax or chest tube placement. In our cohort, which had a high prevalence of small lesions, saline sealing alone may be insufficient to reduce post-biopsy pneumothorax risk. Hence, combined strategies require further investigation.

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CASE REPORT
  • Yohei Takeshita, Junji Moriya, Yo Matsui, Shintaro Chiba
    Article type: CASE REPORT
    2025Volume 10 Pages e2025-0083
    Published: December 29, 2025
    Released on J-STAGE: December 29, 2025
    JOURNAL OPEN ACCESS

    Gastric variceal rupture requires rapid hemostasis. When an abdominal balloon catheter is unavailable, alternatives are needed. We report emergency plug-assisted retrograde transvenous obliteration performed with a 9-Fr Optimo balloon-guiding catheter in a 59-year-old man with alcoholic cirrhosis and fundal gastric varices. Under balloon occlusion, balloon-occluded retrograde transvenous venography delineated the variceal complex. A 10-mm Amplatzer Vascular Plug II was deployed via the Optimo, followed by stepwise injection of gelatin sponge particles through a high-flow microcatheter. Complete occlusion was achieved without complications. Follow-up computed tomography and endoscopy confirmed improvement. The Optimo enabled single-system balloon-occluded retrograde transvenous venography, plug deployment, and embolic delivery through one venous access, offering a practical option for urgent hemostasis when inventory constraints exist, provided that preprocedural computed tomography confirms device compatibility.

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ORIGINAL RESEARCH
  • Takeshi Suzuki, Kenkichi Michimoto, Todd Graham, Maofeng Gong, Prem Si ...
    Article type: ORIGINAL RESEARCH
    2025Volume 10 Pages e2025-0054
    Published: December 02, 2025
    Released on J-STAGE: December 02, 2025
    JOURNAL OPEN ACCESS

    Purpose: To evaluate the feasibility of a bilateral flank subcutaneous rat tumor model perfused by the iliolumbar artery, as a reproducible platform for preclinical transarterial therapy research.

    Material and Methods: Eighteen male Lewis rats (median body weight: 295 g; interquartile range: 289-301 g) received bilateral flank implantation of tumor fragments from a pancreatic ductal adenocarcinoma (DSL-6A/C1) that had developed subcutaneously in a donor rat. Upon reaching ≥8 mm in diameter, rats underwent angiography via tail artery access. A microcatheter was advanced into the iliolumbar artery through the aorta, and digital subtraction angiography was used to assess tumor staining. In two animals, either isosulfan blue or fluorescent-labeled nanoparticles were selectively injected via the iliolumbar artery to corroborate radiographic assessment of tumor perfusion. The animal that received fluorescent-labeled nanoparticles was euthanized 24 hours after injection for near-infrared imaging. The remaining rats underwent embolization and were monitored for 72 hours to assess safety.

    Results: The tumor engraftment rate was 97.2% (35/36). Selective iliolumbar artery catheterization was successful in all rats (100%), with a median procedure time of 20 minutes (interquartile range: 15-25). Digital subtraction angiography confirmed tumor staining in all of the evaluable tumors. Isosulfan blue injection via the iliolumbar artery resulted in whole-tumor staining. Fluorescence imaging revealed higher fluorescent signal intensity in the treated tumor compared with the contralateral side. No major complications, including skin ischemia, claudication, or paralysis were observed.

    Conclusions: This minimally-invasive model allows for highly reproducible subcutaneous tumor engraftment and reliable selective iliolumbar artery catheterization, providing a straightforward, technically feasible, and practical platform for transarterial therapy studies in rats.

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CASE REPORT
  • Takayuki Sanomura, Takashi Norikane, Katsuya Mitamura, Riku Morita, Ha ...
    Article type: CASE REPORT
    2025Volume 10 Pages e2025-0059
    Published: December 02, 2025
    Released on J-STAGE: December 02, 2025
    JOURNAL OPEN ACCESS

    Median arcuate ligament syndrome is a rare condition that can lead to aneurysm formation in collateral vessels due to celiac artery compression. While pancreaticoduodenal artery aneurysms are common, esophageal artery aneurysms are extremely rare. We report a case of a ruptured proper esophageal artery aneurysm associated with median arcuate ligament syndrome in a 61-year-old woman. Emergency transarterial embolization using N-butyl 2-cyanoacrylate was performed successfully via the afferent artery. Follow-up imaging confirmed effective embolization with preserved esophageal perfusion and no signs of ischemia. This case highlights the importance of recognizing rare aneurysm sites in median arcuate ligament syndrome, and supports N-butyl 2-cyanoacrylate embolization as a safe and effective treatment for esophageal artery aneurysms.

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  • Kai Seng Loi, Ridzuan Abdul Rahim
    Article type: CASE REPORT
    2025Volume 10 Pages e2025-0058
    Published: December 02, 2025
    Released on J-STAGE: December 02, 2025
    JOURNAL OPEN ACCESS

    We present a novel salvage technique for managing a completely occluded percutaneous nephrostomy catheter in a patient with metastatic cervical cancer and bilateral obstructive uropathy. While the left nephrostomy catheter was exchanged uneventfully, the right was entirely blocked, preventing standard guidewire passage. Using the Accustick II Introducer System (Boston Scientific, Spencer, IN, USA), a 21-gauge needle was advanced through the cut percutaneous nephrostomy lumen to traverse the obstruction, penetrating the catheter sidewall and access the renal collecting system. This allowed sequential guidewire and sheath introduction, enabling successful percutaneous nephrostomy replacement through the existing tract. Termed the Sharp Urologic Recanalization technique, this method modernizes traditional sharp recanalization strategies and offers a less invasive alternative when conventional techniques fail.

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  • Jun Kiat Ho, Jasmine Ming Er Chua, Damian Ong, Chow Wei Too
    Article type: CASE REPORT
    2025Volume 10 Pages e2024-0055
    Published: December 02, 2025
    Released on J-STAGE: December 02, 2025
    JOURNAL OPEN ACCESS

    An 83-year-old man presented with chronic right shoulder pain and stiffness from recurrent subacromial-subdeltoid bursitis associated with rotator cuff tears, despite initial conservative measures. He refused surgery but agreed to transarterial embolization.

    The first transarterial embolization was performed with 1:1 lipiodol:iohexol emulsion, but provided no significant symptom relief. A repeat transarterial embolization demonstrated recanalization in several branches and new neovascularity. These were successfully embolized with 100 μm embozene particles. Post-procedure, his pain score on the numerical rating scale improved from 6 to 2 at rest and 7 to 3 during motion, no longer requiring regular analgesics. Follow-up ultrasound showed sustained resolution of bursal effusion up to 18 months.

    This case suggests the efficacy of transarterial embolization in treating recurrent subacromial-subdeltoid bursitis.

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PICTORIAL ESSAY
  • Shiro Miyayama, Masashi Yamashiro, Rie Ikeda, Takumi Sugiura, Seitaro ...
    Article type: PICTORIAL ESSAY
    2025Volume 10 Pages e2025-0013
    Published: November 14, 2025
    Released on J-STAGE: November 14, 2025
    JOURNAL OPEN ACCESS
    Supplementary material

    Percutaneous interventions are widely performed for bile duct injuries due to surgery, trauma, and local ablation or transarterial chemoembolization for hepatocellular carcinoma. Most bilomas can be treated with percutaneous drainage alone, but additional biliary drainage or plastic stenting in the common bile duct, dilation of the coexisting biliary stricture, or embosclerosis is also required for refractory bilomas. For bile duct occlusions or disruptions, percutaneous transhepatic biliary drainage and long-term catheter placement across the affected segment are recommended. In addition, intrahepatic biliary ablation and/or percutaneous transhepatic portal vein embolization is effective for refractory bile leaks. Percutaneous drainage is required for infected necrotized hepatocellular carcinoma due to ascending cholangitis after transarterial chemoembolization. Plastic stent placement is also recommended for main bile duct strictures caused by transarterial chemoembolization.

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TECHNICAL NOTE
  • Soichiro Okamoto, Yusuke Matsui, Takahiro Kawabata, Koji Tomita, Kazua ...
    Article type: TECHNICAL NOTE
    2025Volume 10 Pages e2025-0034
    Published: October 31, 2025
    Released on J-STAGE: October 31, 2025
    JOURNAL OPEN ACCESS

    Purpose: To determine the optimal virtual-target definition for detecting renal cell carcinoma feeders using transarterial computed tomography angiography with automated feeder-detection software.

    Material and Methods: This retrospective study included 17 patients with 17 renal cell carcinomas who underwent transarterial ethiodized-oil marking before cryoablation. Tumor feeders were automatically detected on transarterial renal computed tomography angiography images using the automated feeder-detection software with three virtual-target definitions: small (ellipsoidal area maximized within the tumor contour), medium (ellipsoidal area covering the entire tumor with a minimal peripheral margin), and large (ellipsoidal area including the tumor and a 5-mm peripheral margin). The detected feeders were classified as true or false positives according to the findings of selective renal arteriography, by consensus of two interventional radiologists. Feeder-detection sensitivity and the mean number of false-positive feeders per tumor were calculated for each virtual-target definition.

    Results: For 17 tumors, 25 feeding arteries were identified on the arteriography. The feeder-detection sensitivity of the software was 80.0% (20/25), 88.0% (22/25), and 48.0% (12/25) for small, medium, and large virtual targets, respectively. The mean ± standard deviation number of false-positive feeders per tumor was 0.82 ± 1.3, 1.41 ± 1.1, and 2.82 ± 1.6 when using small, medium, and large virtual-target definitions, respectively.

    Conclusions: The detection rate of renal cell carcinoma feeders with the automated feeder-detection software varies according to the virtual-target definition. Using a medium virtual target, covering the entire tumor with a minimal peripheral margin, may provide the highest sensitivity and an acceptable number of false-positive feeders.

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CASE REPORT
  • Pui Man Chung, King Shing Yung, Dominic So, Stephen Ka Hon Wong, Lik F ...
    Article type: CASE REPORT
    2025Volume 10 Pages e2025-0005
    Published: October 31, 2025
    Released on J-STAGE: October 31, 2025
    JOURNAL OPEN ACCESS

    We report a case of a large pheochromocytoma in a middle-aged woman with a good past health record. She presented with pheochromocytoma crisis, complaining of acute shortness of breath, and quickly deteriorated into refractory cardiogenic shock with multiorgan failure. Multi-axial CT showed a large mass in the left suprarenal region. Elevated serum catecholamines confirmed the diagnosis of pheochromocytoma. Left distal transradial adrenal artery embolization under local anesthesia was performed because of limited femoral access and very high perioperative risk. The aim was to devascularize the tumor and reduce catecholamine secretion. Her labile blood pressure improved after embolization. She gradually recovered and underwent adrenalectomy three weeks later.

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TECHNICAL NOTE
  • Nobuyuki Higashino, Tetsuo Sonomura, Nobuyuki Kawai, Kodai Fukuda, Hir ...
    Article type: TECHNICAL NOTE
    2025Volume 10 Pages e2025-0022
    Published: October 31, 2025
    Released on J-STAGE: October 31, 2025
    JOURNAL OPEN ACCESS

    Purpose: To investigate the optimal order of mixing N-butyl-2-cyanoacrylate-Lipiodol-iodine contrast materials (N-butyl cyanoacrylate-Lipiodol-iodinated contrast material).

    Materials and Methods: Lipiodol was used as an oil-based contrast material. Three types of water-soluble iodinated contrast materials were used: iopamidol, iohexol, and iomeprol. The materials were mixed in three different orders: N-butyl cyanoacrylate-Lipiodol-iodinated contrast material, in which N-butyl-2-cyanoacrylate was first mixed with Lipiodol and then with iodinated contrast materials; N-butyl cyanoacrylate mixed first with an iodinated contrast material and then with Lipiodol, in which N-butyl-2-cyanoacrylate was first mixed with iodinated contrast material and then with Lipiodol; and Lipiodol mixed first with an iodinated contrast material and then with N-butyl cyanoacrylate, in which Lipiodol was first mixed with iodinated contrast materials and then with N-butyl-2-cyanoacrylate. N-butyl cyanoacrylate-Lipiodol-iodinated contrast material was prepared at two ratios: 2:3:1 (N-butyl cyanoacrylate-Lipiodol-iodinated contrast material 231) and 1:4:1 (N-butyl cyanoacrylate-Lipiodol-iodinated contrast material 141). The particle sizes and injection pressures of the mixtures were measured, and their adhesiveness was evaluated.

    Results:N-butyl cyanoacrylate mixed first with Lipiodol and then with an iodinated contrast material and Lipiodol mixed first with an iodinated contrast material and then with NBCA could be prepared, but N-butyl cyanoacrylate mixed first with Lipiodol and then with an iodinated contrast material could not because of immediate polymerization between N-butyl-2-cyanoacrylate and iodinated contrast material. N-butyl cyanoacrylate mixed first with Lipiodol and then with an iodinated contrast material mixtures had large, irregular particles (33.1-126.5 μm) with non-uniform distribution. Lipiodol mixed first with an iodinated contrast material and then with N-butyl cyanoacrylate mixtures yielded significantly smaller, uniformly distributed particles (1.6-3.3 μm) irrespective of contrast material type. Both Lipiodol mixed first with an iodinated contrast material and then with NBCA and NBCA mixed first with Lipiodol and then with an iodinated contrast material mixtures showed no catheter adhesiveness.

    Conclusions: Lipiodol mixed first with an iodinated contrast material and then with NBCA is an appropriate mixing order because of its uniform particle sizes irrespective of contrast materials, and low adhesiveness compared with other mixtures.

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ORIGINAL RESEARCH
  • Junya Ichiki, Rika Yoshimatsu, Kensuke Osaragi, Marina Osaki, Ryo Hama ...
    Article type: ORIGINAL RESEARCH
    2025Volume 10 Pages e2025-0023
    Published: October 21, 2025
    Released on J-STAGE: October 21, 2025
    JOURNAL OPEN ACCESS

    Purpose: This retrospective study investigated the factors influencing the difficulty and complications of peripherally inserted central catheter insertion.

    Material and Methods: The study evaluated 189 cases of peripherally inserted central catheter insertion (139 patients) performed in our angiography unit from October 2023 to March 2024. Each vein was punctured under ultrasound guidance, and a guidewire and catheter were advanced under fluoroscopic guidance. The patients were classified into two groups based on the procedural time (≤10 minutes [short group] and >10 minutes [long group]), number of punctures, occurrence of procedure-related complications, and performance of venography, and patient characteristics and procedural details were compared in these groups.

    Results: The long group featured a significantly higher proportion of female patients, deeper vessel depth, smaller vessel diameter, and higher proportion of junior residents among the operators than in the short group. The multiple-puncture group had a significantly younger age, higher proportion of female patients, and deeper vessel depth than the single-puncture group. The complication group had a younger age, lower platelet count, and deeper vessels than the non-complication group. The venography group exhibited a significantly smaller vessel diameter than the non-venography group.

    Conclusions: For peripherally inserted central catheter insertion, younger age, female sex, deeper and smaller vessels, and less operator experience were associated with procedural difficulty. Younger age, low platelet counts, and deeper vessels were associated with procedural complications. A smaller vessel diameter was associated with the need for venography. These factors should be considered when selecting the operator, insertion site, method, and operation site to ensure a reliable procedure.

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TECHNICAL NOTE
  • Takumi Sugiura, Akira Yokka, Toru Yamamoto, Kazunori Koyama, Shintaro ...
    Article type: TECHNICAL NOTE
    2025Volume 10 Pages e2025-0030
    Published: October 21, 2025
    Released on J-STAGE: October 21, 2025
    JOURNAL OPEN ACCESS

    Purpose: To evaluate the feasibility of aorto-uni-iliac endovascular aortic repair using the Gore Excluder in selected patients.

    Material and Methods: This retrospective study reviewed five cases of aorto-uni-iliac endovascular aortic repair for abdominal aortic aneurysm using the Gore Excluder between January 2014 and January 2024. Patient demographics, procedural details, and postoperative outcomes were evaluated. Study endpoints included technical success, overall survival, aneurysm sac changes, endoleak occurrence, secondary interventions, and aneurysm-related death to evaluate feasibility and mid-term durability. Technical success was defined as successful stent graft deployment without conversion to open repair.

    Results: The cohort included one elective case in which a dedicated aorto-uni-iliac device was deemed unsuitable, three cases converted intraoperatively from bifurcated to aorto-uni-iliac configuration, and one case in which the dedicated device was unavailable. The aorto-uni-iliac configuration was achieved through off-label use of aortic extenders or an upside-down contralateral leg. All cases were technically successful. Three cases were emergency procedures. All cases required femoro-femoral crossover bypass. Slight type III endoleaks were detected in two cases on completion aortography but had resolved on postoperative computed tomography on days 11 and 16, respectively. No type III endoleaks were observed in any case during follow-up. No aneurysm-related deaths occurred. Over a median follow-up of 35 months (range: 1-62; excluding one same-day death), no sac enlargement was observed, suggesting acceptable durability. Median overall survival was 1,100 days (range: 0-1,966).

    Conclusions: Aorto-uni-iliac endovascular aortic repair using the Gore Excluder for abdominal aortic aneurysm is feasible when dedicated aorto-uni-iliac devices are unavailable or unsuitable, particularly in emergencies.

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ORIGINAL RESEARCH
  • Takeshi Aramaki, Rui Sato, Atsushi Saiga, Kazuhisa Asahara, Takahiro I ...
    Article type: ORIGINAL RESEARCH
    2025Volume 10 Pages e2024-0008
    Published: October 21, 2025
    Released on J-STAGE: October 21, 2025
    JOURNAL OPEN ACCESS

    Purpose: Transarterial chemoembolization for hepatocellular carcinoma can be combined with radiofrequency ablation to improve local control. Radiofrequency ablation is usually performed under ultrasound guidance. Computed tomography can detect lesions in the whole liver, but when performing liver puncture under conventional computed tomography guidance, peripheral intrahepatic vessels cannot be visualized, risking vascular injury. The efficacy and safety of radiofrequency ablation under computed tomography guidance combined with transarterial chemoembolization were evaluated.

    Material and Methods: A total of 186 procedures performed in 142 patients with hepatocellular carcinoma between September 2016 and December 2021, in which radiofrequency ablation was performed under computed tomography guidance combined with transarterial chemoembolization were evaluated. Patient background, survival, local recurrence, adverse events, and post-procedural bleeding were evaluated.

    Results: Overall, 28 women and 114 men (median age, 74 years; age range, 49-90 years) were evaluated. The etiology of hepatocellular carcinoma was hepatitis B, hepatitis C, hepatitis B+C, and hepatitis non-B non-C in 49, 27, 28, and 38 patients, respectively. The Child-Pugh score was 5/6/≥7 in 137/41/8, and modified albumin-bilirubin was 1/2a/2b/3 in 97/45/42/2, respectively. The 1-, 2-, and 3-year overall survival rates were 96.1%, 87.4%, and 74.0%, respectively. Local recurrence developed after 33/186 procedures, and the 1-, 2-, and 3-year local recurrence-free survival rates (per procedure) were 86.4%, 76.6%, and 57.5%, respectively. Post-procedural bleeding occurred in 17/186 procedures; 13 required embolization, and 4 stopped bleeding spontaneously.

    Conclusions: Computed tomography-guided radiofrequency ablation with simultaneous transarterial chemoembolization is a useful treatment for early-stage hepatocellular carcinomas that cannot be detected on ultrasound.

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CASE REPORT
  • Satoshi Oue, Ken Kageyama, Atsushi Jogo, Akira Yamamoto, Kazuki Murai, ...
    Article type: CASE REPORT
    2025Volume 10 Pages e2024-0066
    Published: October 21, 2025
    Released on J-STAGE: October 21, 2025
    JOURNAL OPEN ACCESS
    Supplementary material

    Lymphatic ascites developed in a woman in her fifties after she underwent total hysterectomy, bilateral salpingo-oophorectomy, and lymph node dissection for endometrial carcinoma. Approximately 500-1,000 mL of opalescent fluid was drained daily. Initially, dietary fat restrictions failed to reduce ascites. Two lipiodol lymphangiographies identified leaks from the iliac lymphatic vessels but were only partially successful at occluding these leaks. Octreotide injection and clamping of the drainage tube were attempted without success. On postoperative day 68, a mixture of lipiodol and n-butyl-2-cyanoacrylate was injected to embolize the leakage point, significantly reducing symptoms. The patient was discharged on day 76, and follow-up computed tomography two months later showed complete resolution of ascites. One year after surgery, the patient remained symptom-free.

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TECHNICAL NOTE
  • Pak Lun Lam, Kar Ho Lee, Justin Christopher Ng, Kin Fen Kevin Fung, Da ...
    Article type: TECHNICAL NOTE
    2025Volume 10 Pages e2025-0027
    Published: October 21, 2025
    Released on J-STAGE: October 21, 2025
    JOURNAL OPEN ACCESS

    Purpose: To review the utility of a spring-loaded blunt-tip co-axial needle in improving procedural outcomes when accessing "difficult-to-reach" targets during percutaneous image-guided procedures.

    Material and Methods: In this single-center retrospective study, consecutive adult patients who underwent percutaneous image-guided procedures using a spring-loaded blunt-tip co-axial needle for "difficult-to-reach" targets from January 2021 to December 2024 were reviewed. Clinical information, including demographics and medical history, was recorded. Pre- and post-procedural radiological findings were assessed. Procedural details, modality of image guidance, technical success, and complications were analyzed. Post-procedural follow-up was reviewed.

    Results: A total of 21 patients (median age: 68.0 years, range 33.0-88.0 years; 15 [71.4%] male) were included. Nearly half (n = 10, 47.6%) of the procedures were percutaneous image-guided drainage. One-third (n = 7, 33.3%) were hydrodissection performed for radiofrequency or microwave ablation of tumors. Three (14.3%) were image-guided biopsies. In one patient (4.8%), the needle was used for percutaneous embolization of a type II endoleak after endovascular repair of an enlarging internal iliac artery aneurysm. No procedure-related complication was encountered. In all 21 cases, adjacent organs were avoided, resulting in retained drainage, achieved tumor control with ablation, achieved tissue diagnosis with biopsy, and eliminated endoleak (100% technical success).

    Conclusions: The spring-loaded blunt-tip co-axial needle appeared to be useful in accessing "difficult-to-reach" targets in a variety of percutaneous image-guided procedures, including drainage, hydrodissection, biopsy, and percutaneous embolization of endoleak.

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CASE REPORT
  • Mariko Maebayashi Nakano, Atsushi Jogo, Toshio Kaminou, Yukimasa Sakai ...
    Article type: CASE REPORT
    2025Volume 10 Pages e2025-0002
    Published: September 30, 2025
    Released on J-STAGE: September 30, 2025
    JOURNAL OPEN ACCESS

    This report details a rare case of intraperitoneal bleeding from a failed puncture site during percutaneous trans-splenic portal vein access. A man in his 60s, who had undergone surgery for gallbladder cancer, presented with recurrent melena. Sclerotherapy for hepatopetal ectopic varices in the elevated jejunum loop was attempted using a percutaneous trans-splenic approach due to extrahepatic portal vein obstruction, which led to intraperitoneal bleeding. Despite initial splenic artery embolization, persistent bleeding required embolization of an intra-splenic vein branch. Although percutaneous trans-splenic portal vein access is generally safe, complications such as intraperitoneal bleeding can occur. Previous studies have highlighted the need for splenic artery embolization. However, this case emphasizes the importance of recognizing splenic venous bleeding as a potential complication and underscores the need for comprehensive management strategies.

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TECHNICAL NOTE
  • Yuya Koike, Kenji Motohashi
    Article type: TECHNICAL NOTE
    2025Volume 10 Pages e2025-0012
    Published: September 30, 2025
    Released on J-STAGE: September 30, 2025
    JOURNAL OPEN ACCESS

    Purpose: This study aimed to show balloon dilation of the puncture site as a technique to facilitate insertion of a large-bore sheath in patients undergoing percutaneous endovascular aneurysm repair who have previously undergone femoral cutdowns.

    Materials and Methods: Three patients with prior femoral cutdowns who required percutaneous insertion of a large-bore sheath were included. After ultrasound-guided puncture of the femoral artery and preparation with a Perclose ProGlide suture, attempts to insert a 12F sheath using a dilator were unsuccessful. Consequently, a 5-mm-diameter balloon catheter was used to dilate the puncture site.

    Results: In two patients, the balloon dilation allowed smooth sheath insertion without bleeding complications. Adequate hemostasis was achieved post-procedure. However, in the third patient, despite high-pressure balloon dilation, residual stenosis prevented sheath insertion. The stenosis was attributed to the puncture path crossing vascular sutures from the previous cutdown, leading to a decision to relocate the puncture site, which then allowed successful sheath insertion.

    Conclusion: Balloon dilation at the puncture site is a viable technique for overcoming challenges in sheath insertion during percutaneous endovascular aneurysm repair in patients with previous femoral cutdowns. In cases in which the puncture site cannot be dilated with the use of a balloon, alternative strategies, such as changing the puncture site, are necessary.

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REVIEW
  • Reiko Woodhams, Kaoru Fujii, Yutaro Kurihara, Daigo Ochiai
    Article type: REVIEW
    2025Volume 10 Pages e2025-0014
    Published: September 17, 2025
    Released on J-STAGE: September 17, 2025
    JOURNAL OPEN ACCESS

    The need for interventional radiology in hemostatic strategies for postpartum hemorrhage has been growing as a reliable and hopeful treatment method because of its non-invasive characteristics, high success rate of hemostatic outcomes, and potential to preserve fertility. Moreover, with the global trend of increasing postpartum hemorrhage, interventional radiology is expected to play an important role. An accurate pre-procedural diagnosis of the underlying cause of bleeding, including tone, trauma, tissue, or thrombin, utilizing contrast-enhanced computed tomography and clinical information, is essential for planning the appropriate technical approach to interventional radiology. This study outlines the fundamental aspects of primary postpartum hemorrhage, compares the computed tomography imaging characteristics associated with various causes, and discusses the appropriate procedural choices of interventional radiology based on the identified etiology.

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  • Ryoichi Kitamura, Takaaki Maruhashi
    Article type: REVIEW
    2025Volume 10 Pages e2025-0029
    Published: September 17, 2025
    Released on J-STAGE: September 17, 2025
    JOURNAL OPEN ACCESS

    This review highlights the role of interventional radiology in the management of renal trauma, emphasizing its contributions to imaging-based diagnosis, injury classification, and treatment. It discusses the indications for and clinical outcomes of transcatheter arterial embolization, as well as the management of renal artery dissection and urinary extravasation. Transcatheter arterial embolization has demonstrated favorable outcomes, even in high-grade injuries, and repeat procedures have proven effective for managing rebleeding. Renal artery dissection may be treated with stent placement to preserve renal function. Although urinary extravasation often resolves spontaneously, persistent cases may require ureteral stenting or percutaneous drainage. Additional interventional radiology-based interventions, including embolization and cryoablation, have also been reported. As a minimally invasive, organ-preserving treatment modality, interventional radiology plays a vital role in supporting non-operative management strategies for renal trauma.

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CASE REPORT
  • Shingo Koyama, Yuya Koike, Asako Nogami, Toru Nagata, Shinjiro Aso, Da ...
    Article type: CASE REPORT
    2025Volume 10 Pages e2025-0011
    Published: September 17, 2025
    Released on J-STAGE: September 17, 2025
    JOURNAL OPEN ACCESS

    We report a case of Budd-Chiari syndrome successfully treated with endovascular recanalization of an inferior vena cava occlusion using a modified sharp recanalization technique. A 45-year-old man presented with hepatic dysfunction, and contrast-enhanced computed tomography revealed a 1.5 cm chronic inferior vena cava occlusion. Standard sharp recanalization using the conventional end of a guidewire failed to cross the lesion. Therefore, we reshaped the end of a 0.035-inch guidewire into a sharper form, enabling successful penetration without the use of specialized devices. This modified technique, adapted from peripheral artery interventions, may offer a safer and more cost-effective option for treating fibrotic venous occlusions. Stepwise balloon dilation was subsequently performed to minimize complications. This report highlights the potential utility of a reshaped guidewire end as a practical alternative when the conventional technique fails.

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  • Yuki Himoto, Yasuyuki Onishi, Yuito Michiwaki, Yuichi Tsuji, Tsuyoshi ...
    Article type: CASE REPORT
    2025Volume 10 Pages e2025-0016
    Published: September 17, 2025
    Released on J-STAGE: September 17, 2025
    JOURNAL OPEN ACCESS
    Supplementary material

    Intravascular large B-cell lymphoma is a rare, aggressive lymphoma characterized by intravascular growth. The liver is a common site of involvement. Although liver biopsy provides sufficient tissue for diagnosis and treatment planning, it carries a risk of severe hemorrhage. This report describes the case of a woman in her 50s with intravascular large B-cell lymphoma who developed liver hemorrhage that was uncontrollable by transarterial embolization after undergoing ultrasound-guided percutaneous liver biopsy, necessitating laparoscopic hemostasis. Pathological findings revealed markedly dilated liver sinusoids filled with tumor cells, suggesting direct hemorrhage from these vessels. This case highlights the potential for increased hemorrhage risk in intravascular large B-cell lymphoma and underscores the necessity for careful consideration of alternative biopsy techniques, such as the transjugular approach or percutaneous biopsy with tract embolization.

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GUIDELINE
ORIGINAL RESEARCH
  • Masatomo Ueda, Hidenori Mitani, Yu Nakaki, Hisayuki Kodama, Toshihiro ...
    Article type: ORIGINAL RESEARCH
    2025Volume 10 Pages e2025-0007
    Published: September 03, 2025
    Released on J-STAGE: September 03, 2025
    JOURNAL OPEN ACCESS

    Purpose: To evaluate the performance of automated tumor-feeder detection software in transarterial chemoembolization for hepatocellular carcinoma using angio-computed tomography.

    Material and Methods: This was a retrospective study of 107 hepatocellular carcinomas in 74 patients who underwent selective transarterial chemoembolization between June 2021 and December 2022. Identification of tumor-feeding arteries on computed tomography during hepatic angiography images acquired prior to chemoembolization with angio-computed tomography was evaluated in two independent methods: analysis by automated tumor-feeder detection software and interpretation by radiologists. The sensitivity and positive predictive value of both were calculated, and the sensitivity was compared with the McNemar test. Differences with p <0.05 were considered statistically significant.

    Results: Transarterial chemoembolization was applied to 107 hepatocellular carcinoma tumors fed by 114 arteries. No significant difference was observed in sensitivity between the software and the interpretation of radiologists (90.4% vs. 95.6%, p = 0.15). The positive predictive value for the software was 90.4%; that for the interpretation of radiologists was 86.8%.

    Conclusions: The accuracy of automated tumor-feeder detection software applied to angio-computed tomography was comparable to that of radiologists.

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  • Hiroshi Anai, Toshihiro Tanaka, Hideyuki Nishiofuku, Osamu Ikeda, Dais ...
    Article type: ORIGINAL RESEARCH
    2025Volume 10 Pages e2024-0038
    Published: September 03, 2025
    Released on J-STAGE: September 03, 2025
    JOURNAL OPEN ACCESS

    Purpose: To evaluate the efficacy and safety of the GORE® VIABAHN® Endoprosthesis (stent graft) for traumatic or iatrogenic vessel injury.

    Material and Methods: This prospective, multicenter, cohort study for post-marketing clinical surveillance was conducted in Japan. Efficacy and safety endpoints included successful device implantation, primary and secondary hemostasis of injury, 1-month and 1-year survival rate, and at 1-, 6-, 12-months post-procedure, primary and secondary patency rates, antiplatelet drug administration, and serious adverse events.

    Results: In 37 patients (mean age 73.3±12.5 years; 22 males; 59.5%), 38 vessel injuries were evaluated. Primary treated arteries were visceral, subclavian, and iliac arteries; 86.8% (33/38) were iatrogenic, and 13.2% (5/38) were traumatic vessel injury. Iatrogenic injury included pseudoaneurysm (63.6%), perforation (24.4%), rupture (15.2%), dissection (12.1%), or fistula (3.0%). Technical success in 36 patients (36/37; 97.3%) with 37 vessels (37/38; 97.4%), and primary and secondary hemostasis in all patients were achieved. Primary patency at 1-, 6-, and 12-months was 89.1%, 84.8%, and 80.6%, and secondary patency was 91.5%, 87.3%, and 82.4%, respectively. The Kaplan-Meier survival estimate was 94.4% through 1 month and 75.9% through 1 year. No device-related deaths occurred. Through 12 months, of the 19 serious adverse events (13 patients), three serious adverse events were judged by the investigator to be device-related (vascular stent graft stenosis) or procedure-related (device occlusion and cerebellar infarction).

    Conclusions: The use of the VIABAHN stent graft for vessel injury was safe and effective in this study. Successful hemostasis was achieved through 1 month. Through 1 year, no device-related deaths were reported.

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  • Yoshiki Endo, Hirofumi Sekino, Yoko Nihei, Ryo Yamakuni, Daichi Kuroiw ...
    Article type: ORIGINAL RESEARCH
    2025Volume 10 Pages e2024-0053
    Published: September 03, 2025
    Released on J-STAGE: September 03, 2025
    JOURNAL OPEN ACCESS

    Purpose: To evaluate the sample weights obtained using a new semi-automatic biopsy needle and a new full-core biopsy needle, and to compare them with those obtained using a conventional semi-automatic needle under identical ex vivo conditions.

    Material and Methods: A total of three biopsy needles were compared: the semi-automatic biopsy needles TEMNO Elite™ (Merit Medical Systems, South Jordan, UT, USA) and STARCUT® (TSK Laboratory, Tochigi, Japan) and the full-core automatic biopsy needle CorVocet™ (Merit Medical Systems), with throw lengths of 15 mm, 20 mm, and 25 mm. Two materials were used for sampling: kamaboko (a type of Japanese fish cake) and chicken breast muscle. For each material, 20 specimens were collected using each needle type, resulting in 100 samples per material. All procedures were conducted under identical conditions.

    Results: The TEMNO Elite™ needle yielded the heaviest samples among all tested needles in both kamaboko (9.21 ± 0.95 mg) and chicken breast (5.92 ± 0.51 mg), significantly surpassing all others (p < 0.05). STARCUT® collected significantly more tissue than CorVocet™ (15 mm) in both materials (p < 0.05), while CorVocet™ (25 mm) collected more than STARCUT® in chicken breast (p < 0.05). No significant difference was observed between STARCUT® and CorVocet™ (20 mm) in both materials. For CorVocet™, sample weight increased with throw length in both materials.

    Conclusions: The TEMNO Elite™ needle collected the heaviest biopsy specimens among all tested needles in both model materials.

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CASE REPORT
ORIGINAL RESEARCH
  • Vrishit Saraswat, Soumil Singhal, Anubhav Harish Khandelwal, Anurag Me ...
    Article type: ORIGINAL RESEARCH
    2025Volume 10 Pages e2024-0041
    Published: September 03, 2025
    Released on J-STAGE: September 03, 2025
    JOURNAL OPEN ACCESS

    Purpose: Portal vein thrombosis (PVT), is seen in about 25% of patients with cirrhosis. Chronic portal vein thrombosis can significantly alter anatomy, often leading to the diversion of splanchnic blood into expansive and compliant vascular channels. This process generates extensive collateral networks and large varices that function as portosystemic shunts. Portal cavernous transformation represents a critical vascular condition marked by the formation of a network of collateral veins that develops to bypass an obstructed portal vein [PV]. Given these physiological changes, performing liver transplantation is associated with higher morbidity and mortality rates. We present an early, single-center experience for portal vein reconstruction (PVR) and the creation of a transjugular intrahepatic portosystemic shunt (TIPS) to increase transplant candidacy in such patients.

    Material and Methods: Retrospectively, data was obtained from the Picture Archiving and Communication System (PACS) and Hospital Information System (HIS) from a single center between January 2016 to January 2024. In total, 15 patients with obliterative main portal vein thrombosis were selected. These patients underwent Percutaneous transhepatic portal vein recanalization with transjugular intrahepatic portosystemic shunt to increase their transplant eligibility after a collaborative imaging examination by transplant surgery and interventional radiology team. Up until liver transplant LT, patients were monitored in the hepatology/transplant clinic, and thereafter in the posttransplant clinic. To confirm portal vein PV patency, serial ultrasound/Dynamic computed tomography/magnetic resonance imaging was done.

    Results: Portal vein recanalization with transjugular intrahepatic portosystemic shunt was performed in 15 patients. Technical success, defined as the maintenance of patency in both the portal vein and the transjugular intrahepatic portosystemic shunt at the conclusion of the procedure, was achieved in all 15 cases (100%).

    Conclusions: Patients with portal vein thrombosis may significantly benefit from portal vein recanalization with transjugular intrahepatic portosystemic shunt, enhancing transplantation candidacy and facilitating physiologic end-to-end anastomoses.

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REVIEW
  • Shigeo Ichihashi, Daisuke Gotoh, Naoki Fujimura, Yuto Chanoki, Tatsuya ...
    Article type: REVIEW
    2025Volume 10 Pages e2024-0063
    Published: September 03, 2025
    Released on J-STAGE: September 03, 2025
    JOURNAL OPEN ACCESS

    Prostatic artery embolization is a minimally invasive treatment for lower urinary tract symptoms caused by benign prostatic hyperplasia. We report our first case of prostatic artery embolization in a 74-year-old male with urinary retention requiring intermittent catheterization. Bilateral prostatic artery embolization using Embosphere microspheres was successful, with no major complications. By 2 months post-procedure, intermittent catheterization was no longer required, and at 6 months, symptoms and prostate volume showed marked improvement. A review of Asian studies confirmed prostatic artery embolization's safety and efficacy, with clinical success in 78%-100% of cases and technical success rates comparable to those in Western countries. Despite the smaller vessel sizes in Asians, outcomes were unaffected. Prostatic artery embolization appears to be an effective treatment for benign prostatic hyperplasia and requires further validation to support its broader use in Japan.

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CASE REPORT
  • Asako Kuhara, Yasunori Arai, Yohei Takei, Akihito Nakajima, Shuichi Ta ...
    Article type: CASE REPORT
    2025Volume 10 Pages e2025-0009
    Published: August 21, 2025
    Released on J-STAGE: August 21, 2025
    JOURNAL OPEN ACCESS
    Supplementary material

    This study reports a case of a J-shaped guidewire entrapped in a Chiari network during central venous port insertion. A female patient in her 50s with breast cancer was referred for a single-lumen port placement. The subclavian vein was accessed using an 18 G needle under ultrasound guidance, and a 0.035-inch J-shaped guidewire was passed to the superior vena cava under fluoroscopy. Resistance was encountered in the right atrium when advancing to the inferior vena cava, and the J-shaped guidewire was difficult to retract. The 4F catheter on the J-shaped guidewire was towed, and the J-shaped guidewire was removed despite strong resistance. The removed catheter was significantly deformed, and the J-shaped guidewire tip was entangled in a white, hard tissue, likely a Chiari network. The patient was asymptomatic intra- and postoperatively.

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CASE REPORT
REVIEW
  • Satoru Nagatomi, Daigo Kanamori, Hiroshi Yamamoto
    Article type: REVIEW
    2025Volume 10 Pages e2024-0057
    Published: August 01, 2025
    Released on J-STAGE: August 01, 2025
    JOURNAL OPEN ACCESS

    Chronic mesenteric ischemia typically presents with postprandial abdominal pain and weight loss due to atherosclerotic stenosis of mesenteric arteries. Endovascular treatment has become the first-line management, demonstrating lower early mortality and fewer complications compared to open surgery. Recent evidence shows that covered stents provide superior long-term outcomes, with better primary patency and freedom from reintervention than bare-metal stents. While patient selection remains crucial, with endovascular treatment being preferred for older, higher-risk patients and shorter lesions, it offers shorter hospital stays and comparable survival rates to open surgery for most patients. This review provides a comprehensive overview of current endovascular management strategies for chronic mesenteric ischemia, including patient selection, technical considerations, and outcomes.

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CASE REPORT
  • Mizuho Ishii, Shinji Wada, Yusuke Satta, Kazunari Nakahara, Kazuki Has ...
    Article type: CASE REPORT
    2025Volume 10 Pages e2024-0023
    Published: August 01, 2025
    Released on J-STAGE: August 01, 2025
    JOURNAL OPEN ACCESS

    Endoscopic ultrasonography-guided biliary drainage has been reported as an alternative technique when transpapillary endoscopic biliary drainage fails. This case study describes a case of pseudoaneurysm, one of the complications unique to endoscopic ultrasonography-guided biliary drainage. An 87-year-old woman who underwent endoscopic ultrasonography-guided hepaticojejunostomy with a partially covered metallic stent developed hematochezia. Contrast-enhanced computed tomography revealed a pseudoaneurysm of the left hepatic artery adjacent to the stent. During coil embolization, angiography revealed bleeding, passing through the covered portion of the stent into the jejunum, and coil embolization was successfully performed. In cases after bile duct stent placement, where a tamponade effect can be expected, hepatic artery pseudoaneurysm may occur as a complication of puncture, and embolization may be required.

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REVIEW
  • Hidehiko Taguchi, Shigeo Ichihashi, Natsuhiko Saito, Hiroshi Okada, To ...
    Article type: REVIEW
    2025Volume 10 Pages e2024-0060
    Published: August 01, 2025
    Released on J-STAGE: August 01, 2025
    JOURNAL OPEN ACCESS

    Vascular access dysfunction remains a significant challenge in hemodialysis patients, primarily caused by stenosis and occlusion in arteriovenous fistulas and grafts. Recent advancements in percutaneous transluminal angioplasty have introduced innovative tools such as drug-coated balloons and stent grafts. Drug-coated balloons enhance patency by reducing neointimal hyperplasia through localized drug delivery, with superior outcomes demonstrated in randomized controlled trials. Stent grafts provide structural support and mitigates restenosis at venous anastomoses but faces challenges in maintaining long-term patency. Cutting balloons, a well-established device, offer a unique mechanism of controlled fibroelastic disruption, making them effective for resistant stenoses. This review evaluates the clinical impact of these devices, focusing on evidence from Japan, and emphasizes the importance of selecting the appropriate device based on individual lesion characteristics.

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TECHNICAL NOTE
  • Shohei Toyoda, Arisa Kameda, Yasushi Fukuoka, Hiroyuki Takada, Kentaro ...
    Article type: TECHNICAL NOTE
    2025Volume 10 Pages e2025-0004
    Published: August 01, 2025
    Released on J-STAGE: August 01, 2025
    JOURNAL OPEN ACCESS

    Purpose: A newly developed device, the Partially Automated Needle Direction Assistant, was designed to assist with computed tomography-guided oblique needle puncture. This device allows operators to accurately and in real-time determine the puncture angle based on the target lesion and needle entry point. The purpose of this report is to introduce the concept of Partially Automated Needle Direction Assistant and present results from an initial phantom study.

    Material and Methods: Partially Automated Needle Direction Assistant integrates a 9-axis internal measurement unit for angle detection, transmitting real-time orientation data to a tablet application via Wi-Fi. Operators align the needle direction with a displayed guideline. A phantom study was conducted with two operators of differing interventional radiology experience levels (operator A: 1 year; operator B: 4 years) performing needle punctures into embedded targets. Success rates were evaluated based on a scoring system reflecting needle placement accuracy.

    Results: Both operators successfully punctured all six sites, achieving a 100% success rate. Center hits were not influenced by target size, puncture direction, or operator experience level. Operator A tended to achieve higher scores than operator B (mean scores: 1.50 vs. 1.17; p = 0.073).

    Conclusions: Partially Automated Needle Direction Assistant demonstrated high accuracy and usability in guiding oblique needle punctures, regardless of operator experience. This device has the potential to enhance safety, reduce radiation exposure, and streamline computed tomography-guided interventions.

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ORIGINAL RESEARCH
  • Shunsuke Sugawara, Shintaro Kimura, Miyuki Sone, Chihiro Itou, Yuji Ko ...
    Article type: ORIGINAL RESEARCH
    2025Volume 10 Pages e2025-0003
    Published: August 01, 2025
    Released on J-STAGE: August 01, 2025
    JOURNAL OPEN ACCESS

    Purpose: To determine how the anatomical morphology of the left subclavian artery and aortic arch affects the technical difficulty of navigating the aortic arch during left transradial access for visceral vascular interventions.

    Material and Methods: We retrospectively evaluated 98 patients who underwent visceral vascular interventions using left transradial access from January 2022 to December 2022. Cannulation of the descending aorta was considered difficult when the time required to manipulate the catheter in the aortic arch exceeded 30 seconds. The morphologies of the left subclavian artery and aortic arch were evaluated by measuring [1] the angle between the left subclavian artery to the apex of the aortic arch, [2] the angle of incidence of the left subclavian artery in the horizontal direction, and [3] the distance from the left edge of the left subclavian artery origin to the apex of the aortic arch using computed tomography images. The values of [1], [2], and [3] were evaluated using the Mann-Whitney U test.

    Results: The median and mean catheterization times were 26 seconds (range, 2-1,312) and 112.4 ± 226.0 seconds, respectively. For difficult (n = 44) and not-difficult (n = 54) cases, the mean values of [1], [2], and [3] were 111.8° vs. 140.8° (p < 0.001), 67.3° vs. 76.9° (p < 0.001), and 27.5 mm vs. 24.7 mm (p = 0.001), respectively.

    Conclusions: Technical difficulty in passing the aortic arch during left transradial access is more likely in patients with steep angles of the left subclavian artery or steep angles between the left subclavian artery and the apex of the aortic arch.

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ORIGINAL RESEARCH
  • Hidemasa Kubo, Atsushi Saiga, Rui Sato, Shimpei Otsuka, Ryo Ashida, Ka ...
    Article type: ORIGINAL RESEARCH
    2025Volume 10 Pages e2024-0044
    Published: July 23, 2025
    Released on J-STAGE: July 23, 2025
    JOURNAL OPEN ACCESS

    Purpose: Standard methods for percutaneous transhepatic portal vein embolization have not yet been established. This study aimed to elucidate the effectiveness of balloon occlusion in percutaneous transhepatic portal vein embolization using gelatin sponges on the hypertrophy ratio of the future liver remnant volume.

    Material and Methods: This retrospective study included 93 patients who underwent percutaneous transhepatic portal vein embolization for right hepatectomy between January 2018 and September 2022. Based on the embolization procedure, patients were divided into a balloon group (n = 13) and a non-balloon group (n = 80). The clinical factors and future liver remnant volume hypertrophy ratios were compared. Moreover, significant factors associated with the future liver remnant volume hypertrophy ratio between the groups were analyzed.

    Results: The future liver remnant volume hypertrophy ratio was significantly higher in the balloon group than in the non-balloon group (1.44 [interquartile range, 1.37-1.89] vs. 1.29 [1.15-1.46], p = 0.011). The initial future liver remnant volume (289 [interquartile range, 259-454] vs. 400 [324-479] mL, p = 0.036) and number of gelatin sponge sheets (5 [interquartile range, 5-6] vs. 4 [3-5], p = 0.008) significantly differed. However, recanalization and severe complications were not different between groups. According to the multivariate linear regression analysis, diabetes mellitus (coefficient, −0.202, p = 0.009), initial future liver remnant volume (coefficient, −0.001, p < 0.001), and balloon occlusion (coefficient, 0.228, p = 0.007) were independent factors affecting the future liver remnant volume hypertrophy ratio.

    Conclusions: Balloon occlusion may be effective in future liver remnant volume hypertrophy in percutaneous transhepatic portal vein embolization using gelatin sponges.

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CASE REPORT
  • Mitsuhiro Kishino, Ryo Wakejima, Masami Ito, Ayumi Yamada, Takuya Adac ...
    Article type: CASE REPORT
    2025Volume 10 Pages e2024-0049
    Published: July 23, 2025
    Released on J-STAGE: July 23, 2025
    JOURNAL OPEN ACCESS

    Thoracic duct embolization has emerged as an alternative treatment for refractory chylothorax, in addition to thoracic duct ligation. Thoracic duct embolization is typically performed via direct puncture of the cisterna chyli and cannulation of the thoracic duct, or via a retrograde approach to the thoracic duct through the venous angle. The former requires a long puncture through abdominal organs; the latter has anatomical limitations depending on the case. The reported success rates of both approaches are insufficient to provide a complete solution. We report a case of refractory chylothorax successfully treated with thoracic duct embolization using a catheter inserted through a chest tube to cannulate the leaking stump of the thoracic duct. This technique offers a less invasive treatment option that avoids additional punctures or surgical intervention.

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ORIGINAL RESEARCH
  • Masae Deguchi, Tetsuo Sonomura, Hirotatsu Sato, Atsufumi Kamisako, Nob ...
    Article type: ORIGINAL RESEARCH
    2025Volume 10 Pages e2024-0051
    Published: July 23, 2025
    Released on J-STAGE: July 23, 2025
    JOURNAL OPEN ACCESS

    Purpose: We retrospectively analyzed the effect of coil type on the number of coils used and the procedure time in pre-Fontan coil embolization of collateral arteries.

    Material and Methods: Twelve patients with congenital heart disease underwent coil embolization before Fontan surgery between 2010 and 2021. They were divided into 2 groups. Group A comprised 6 patients who underwent coil embolization before the introduction of longer microcoils (≥30 cm) and group B comprised 6 patients who underwent embolization after the introduction of the microcoils. The primary endpoints (number of coils used, embolized area per patient and the internal thoracic artery, and procedure time) were compared between the 2 groups.

    Results: The number of coils used per patient and internal thoracic artery (groups A vs. B: 36.5 vs. 18; p = 0.036, 11.7 vs 7.4; p = 0.047) and the procedure time (247 vs 180 minutes; p = 0.002) were significantly smaller in group B than in group A. The embolized area per internal thoracic artery was significantly larger in group B than in group A (45 vs. 93.5; p < 0.001). All patients underwent Fontan surgery at a mean of 24 days after embolization. Fontan circulation was established in nine of 12 patients. There were no major complications in either group.

    Conclusions: In pre-Fontan coil embolization, a combination of longer microcoils (≥30 cm) may help reduce the number of coils used and the procedure time, which may decrease the health care cost and radiation exposure.

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CASE REPORT
  • Naotoshi Hatsuda, Yasuyuki Onishi, Hironori Shimizu, Mika Nakano, Haru ...
    Article type: CASE REPORT
    2025Volume 10 Pages e2024-0047
    Published: June 30, 2025
    Released on J-STAGE: June 30, 2025
    JOURNAL OPEN ACCESS

    An 89-year-old woman presented with altered mental status. Computed tomography revealed multiple shunts between the portal (segment 3) and hepatic veins (left and middle hepatic veins); detailed vascular anatomy of the shunts could not be determined owing to its complexity. Blood tests revealed an elevated ammonia level. The patient was diagnosed with hepatic encephalopathy secondary to an intrahepatic portosystemic venous shunt. Transcatheter embolization was performed after unsuccessful conservative treatment. The peripheral left and middle hepatic veins downstream of the shunt vessels were embolized through an internal jugular vein approach using Amplatzer vascular plugs and coils. Computed tomography conducted 1 week later indicated occlusion of the shunts. The patient's ammonia levels were normalized. Thus, transcatheter embolization can be useful for treating complex intrahepatic portosystemic venous shunts causing hepatic encephalopathy.

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REVIEW
ORIGINAL RESEARCH
  • Hirokazu Ashida, Shunsuke Kisaki, Kenkichi Michimoto, Hideomi Yamauchi ...
    Article type: ORIGINAL RESEARCH
    2025Volume 10 Pages e2024-0031
    Published: June 13, 2025
    Released on J-STAGE: June 13, 2025
    JOURNAL OPEN ACCESS

    Purpose: To investigate the risk factors for local maxillary sinus squamous cell carcinoma recurrence/residual tumor after superselective intra-arterial cisplatin infusion and concomitant radiotherapy.

    Material and Methods: The protocol of superselective intra-arterial cisplatin infusion and concomitant radiotherapy was as follows: cisplatin was administered once per week for 7 weeks, and the dose of every procedure was 100 mg/m2. Radiation was administered during the same period using intensity-modulated radiation therapy, with a total dose of 70 Gy (2 Gy/35 fractions). The risk factors for local recurrence/residual tumor were retrospectively analyzed using the Cox hazard model in 31 advanced primary maxillary sinus squamous cell carcinoma cases treated with superselective intra-arterial cisplatin infusion and concomitant radiotherapy from October 2016 to 2022. The analyzed risk factors were age, sex, T- and N-factors, invasion of the pterygoid muscle, tumor heterogeneity on imaging modality, tumor signal intensity on diffusion-weighted imaging (b = 1000), tumor-brain stem signal ratio on diffusion-weighted imaging (b = 1000), therapeutic response after the fourth infusion, and complete superselective intra-arterial cisplatin infusion and concomitant radiotherapy or not. We also compared overall survival between the recurrence/residual tumor and non-recurrence groups.

    Results: This study included 31 patients. Non-complete superselective intra-arterial cisplatin infusion and concomitant radiotherapy was the only risk factor that showed a statistically significant difference among all the analyzed risk factors. Overall survival was favorable in the non-recurrence/residual tumor group; however, there was no statistical difference compared to the recurrence/residual tumor group.

    Conclusions: Complete superselective intra-arterial cisplatin infusion and concomitant radiotherapy was the only factor that prevented local recurrence/residual tumor. Therefore, all health careers involved in superselective intra-arterial cisplatin infusion and concomitant radiotherapy should avoid interrupting whenever possible.

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CASE REPORT
  • Chika Somagawa, Hideki Ishimaru, Yoichi Morofuji, Taiga Oka, Satomi Yo ...
    Article type: CASE REPORT
    2025Volume 10 Pages e2024-0034
    Published: June 13, 2025
    Released on J-STAGE: June 13, 2025
    JOURNAL OPEN ACCESS

    A 74-year-old man who had received Bacillus Calmette-Guérin therapy for bladder cancer developed vasovagal syncope. Contrast-enhanced computed tomography showed multiple pseudoaneurysms in the left internal carotid artery, aorta, and right common femoral artery, which were considered to be infected aneurysms. Parent artery occlusion was planned for the left internal carotid artery, but the balloon occlusion test was not possible because of the patient's restlessness; therefore, the patient was treated with a Viabahn stent graft. Approximately 1 month later, another ruptured pseudoaneurysm occurred in the right internal carotid artery, which was also treated with a Viabahn stent graft. The patient did not experience rebleeding or complications such as cerebral infarction. Viabahn may be an effective alternative for the management of carotid artery-infected aneurysms.

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  • Hiroshi Baba, Katsuki Oji, Norio Hongo, Hiroyuki Fujinami, Tadasuke An ...
    Article type: CASE REPORT
    2025Volume 10 Pages e2024-0064
    Published: June 13, 2025
    Released on J-STAGE: June 13, 2025
    JOURNAL OPEN ACCESS

    This case report describes a 56-year-old woman with autosomal dominant polycystic kidney disease and chronic renal failure who underwent transcatheter arterial embolization with N-butyl-2-cyanoacrylate-Lipiodol before renal transplantation. Both kidneys were significantly enlarged, necessitating transcatheter arterial embolization to reduce renal volume and create space for transplantation. The right kidney volume decreased from 2520 to 1150 mL within 9 months after transcatheter arterial embolization, enabling successful transplantation. Long-term (37 months) follow-up demonstrated continued shrinkage of the transcatheter arterial embolization-treated right kidney and a spontaneous reduction in the non-transcatheter arterial embolization-treated left kidney. The reduction in renal volume achieved with transcatheter arterial embolization exceeded that reported for conventional methods using metal coils or ethanol. This case highlights the potential of as an effective embolizing agent for patients with autosomal dominant polycystic kidney undergoing renal transplantation.

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ORIGINAL RESEARCH
  • Yuichi Miyake, Takafumi Yonemitsu, Nozomu Shima, Kodai Fukuda, Tomoya ...
    Article type: ORIGINAL RESEARCH
    2025Volume 10 Pages e2024-0068
    Published: June 13, 2025
    Released on J-STAGE: June 13, 2025
    JOURNAL OPEN ACCESS

    Purpose: N-butyl cyanoacrylate is a liquid embolic material used to treat bleeding. Rebleeding may occur after N-butyl cyanoacrylate embolization due to vasospasm and dilation of the embolized artery. However, the impact of vasospasm on N-butyl cyanoacrylate embolization has not been fully investigated. Therefore, we investigated the impact of vasospasm on the effects of N-butyl cyanoacrylate embolization in swine arteries.

    Material and Methods: Using a swine bleeding model, 24 arteries (hepatic/splenic/both renal/cranial mesenteric) in 5 swine were divided into vasoactive and control groups. The recanalization rates after embolization with 20% N-butyl cyanoacrylate and the volume of N-butyl cyanoacrylate used for embolization were compared between the 2 groups. Arteries in the vasoactive group were constricted by constant venous infusion of vasopressin and an arterial injection of noradrenaline just before embolization and then dilated by arterial injection of papaverine and lidocaine immediately after embolization. Angiography was performed to evaluate recanalization of the embolized arteries immediately and at 5, 15, 30, 45, and 60 minutes after embolization. Recanalization was defined as complete recanalization within 60 minutes or partial recanalization at 60 minutes.

    Results: Angiography revealed recanalization in a significantly greater proportion of arteries in the vasospasm group (11/12 arteries [91.7%]) than in the control group (2/12 arteries [16.7%]) (p = 0.0006). The median volume of N-butyl cyanoacrylate used during embolization was significantly lower in the vasoactive group (0.32 mL) than in the control group (0.78 mL) (p = 0.0037).

    Conclusions: Vasospasm during N-butyl cyanoacrylate embolization increased the recanalization rate of the embolized arteries and reduced the embolization effect in swine.

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CASE REPORT
REVIEW
  • Satoru Nagatomi, Daigo Kanamori, Hiroshi Yamamoto
    Article type: REVIEW
    2025Volume 10 Pages e2024-0039
    Published: April 25, 2025
    Released on J-STAGE: April 25, 2025
    JOURNAL OPEN ACCESS

    Endoleak is a significant complication of endovascular aortic repair, associated with adverse long-term outcomes. This review discusses the classification, mechanisms, and imaging diagnosis of endoleaks. Five types of endoleaks are described, each with distinct characteristics and management approaches. Imaging modalities for endoleak detection include computed tomography, magnetic resonance imaging, ultrasonography, and angiography, each with unique advantages and limitations. Computed tomography remains the gold standard, but magnetic resonance imaging and contrast-enhanced ultrasound show promise in specific scenarios. The article details imaging findings for each endoleak type, emphasizing the importance of multimodality imaging for accurate diagnosis. While computed tomography is essential for early postoperative evaluation and reintervention planning, a tailored approach using various imaging techniques may optimize long-term surveillance. Future research should focus on establishing cost-effective, radiation-minimizing protocols for lifelong post-endovascular aortic repair monitoring.

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