妊婦肺結核症の転帰に関する臨床的研究

抄録

For the purpose of investigating the prognosis of tuberculous pregnant women undergoing chemotherapy, comparative studies were made periodically on vital capacity, erythrocyte sedimentation rate (referred as ESR, hereafter), bodyweight and excretion in tuberculous pregnant women and in 10 control healthy pregnant women from the 6th month of pregnancy to 12th month post partum. As a result the following conclusions were obtained: 1) Vital capacity and ESR.: In the healthy group (A) and in the tuberculous group (B) both the indices changed almost in parallel during the whole course of the experiment.
2) Body weight: Until the 6th month of pregnancy body weight changed almost in parallel in (A) and (B) groups. However, 12 months after delivery a slight increase was noted in (A) group, while the minimum value during the whole course was encountered in (B) group. On the other hand, a tendency of body weight to fall was manifested in both the groups during the period of childbirth and of succeeding lactation and puericulture.
3) Roentgenography of the chest: (B) group consisted of one moderately advanced case and 9 minimal cases according to the classification of the N. T. A., the former having a solitary cavity of the size of a pigeon egg. One year after delivery the moderately advanced case revealed an exacerbation, while out of the 9 cases of minimal disturbances 4 showed an improvement and 5 were unchanged.
4) Examination for mycobacterium tuberculosis: In all of the 10 cases of (B) group negative results were obtained with smear preparation, but many colonies were detected from the moderately advanced case and 1/2 colony was found from one of the minimal cases by means of culture method. As for the process thereafter the moderately advanced case demonstrated no change until 12 months after delivery, while one of the minimal cases turned negative from the 8th month of pregnancy. The other 8 cases were negative throughout this experiment.
5) From the result obtained in the present experiment it was found that the prognosis of the 9 tuberculous pregnant women undergoing chemotherapy, excluding the one case of the open tuberculosis with a cavity, was good at least 12 months after pregnancy similarly to that of healthy pregnant women.
6) The type of pulmonary tuberculosis is, of course, an important factor determing the prognosis of the tuberculous pregnant female.
However, attention should be paid to the fact, hereafter, that such unch unfavorable living conditions as overwork or deficiency in nourishment and sleep during the period of parturition and puericulture is another factor influencing the prognosis for a long period after delivery.