抄録
1) Results of the chest X-ray survey for pulmonary tuberculosis combined with the parasitological examination for paragonimiasis among the school children in Ehime prefecture.
Mass examination against pulmonary tuberculosis combined with screening test for paragonimiasis were carried out 1957, for 4, 371 school children in endemic area of paragonimiasis. Results were as follows, a) 5.3% was positive for intra dermal test with V. B. S. antigen, and 2.5% was doubutful. b) 28.6% out of the positive cases and 1.8% out of doubtful cases for intradermal test were positive for egg test. c) Besides 101 out of 4, 371 showed radiological change in chest X-ray pictures. Out of 101, 55 (54.5%) showed calcified shadows, 34 (33.7%) were proved as paragonimiasis, only 2 were diagnosed as pulmonary tuberculosis. Next, in 1960, a big scale T. B. mass survey by chest X-ray examination were carried out for 24, 686 school children of 45 middle and primary school which were lccated along main rivers in Ehime prefecture. All children who showed radiological changes in direct chest X-ray picture were further examined to detect mainly pulmonary paragonimiasis. Results were as follows. a) 175 (0.71%) out of 24, 686 school children showed radiological changes in chest pictures. Out of 173, 65 (37.6%) were positive and doubtful for intradermal test of paragonimiasis, out of 63, 40 (63.5%) were positive for egg test. Namely, out of 173, 40 (23.1%) were proved as paragonimiasis.
From the above results, it is necessary that T. B. mass survey must be carried out together with screening test for paragonimiasis, especially in the endemic area.
2) Radiological findings of pulmonary paragonimiasis.
Its radiological findings is similar to those of pulmonary tuberculosis. But its changes can be characterized. Of course, to determine the diagnosis of paragonimiasis, it is necessary to clear for eggs in sputa or stools. But when we find doubtful radiological changes in chest X-ray, should further examine with screening test of paragonimiasis, and we can determine the diagnosis of paragonimiasis.
3) On the treatment of pulmonary paragonimiasis with Bithionol.
In 1961, 23 cases of pulmonary paragonimiasis received treatment with Bitin (Bithionol) in Ehime National Sanatorium. Namely, out of 23, 12 were given Bitin in the daily dose of 50mg/kg every other day, 11 were given 40mg kg. And all cases were received 15 daily doses. Results were as follows, a) Effect: All cases were cleared for eggs in the sputa or stools with 1-12 daily doses of Bitin. The followup studies were carried out for 6 months after treatment. All cases continuously were cleared. b) Side-effects: They came out frequently and included the following, such as headache, diarrhea, vomiting, abdominal pain, drug eruption. But almost all of them were mild and transient. 3) Radiological findings: Radiological improvement began soon after treatment, and was remarkable. Namely, at end of treatment, out of 20 infiltrative shadows, 2 showed marked improvement, 10 showed moderate improvement. More, at 3 months after treatment, out of 18, 15 (83.3%) showed marked improvement, and 3 (16.7%) showed moderate improvement.
From the above results, chemotherapy with Bitin has been found to be a very remarkable regimen in the treatment of pulmonary paragonimiasis.
